Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CACNA1H | O95180 | 1/20 | 0.47 |
| ▸ | DRD2 | P14416 | 9/20 | 0.45 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | SIGMAR1 | Q99720 | 3/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | GFER | P55789 | 1/20 | 0.39 |
| ▸ | JAK2 | O60674 | 1/20 | 0.38 |
| ▸ | JAK1 | P23458 | 1/20 | 0.38 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18824271 | 0.91 | CACNA1H (0.47) | CACNA1HDRD2MEN1KMT2AGAA | |
| SCHEMBL18824273 | 0.91 | CACNA1H (0.47) | CACNA1HDRD2MEN1KMT2AGAA | |
| SCHEMBL376023 | 0.82 | ALOX15 (0.32) | — | |
| SCHEMBL13260930 | 0.81 | DRD2 (0.48) | DRD2SIGMAR1 | |
| SCHEMBL376066 | 0.79 | DRD2 (0.42) | CACNA1HDRD2ALDH1A1GFERJAK2 | |
| SCHEMBL31301242 | 0.78 | DRD2 (0.63) | CACNA1HDRD2MEN1KMT2AGAA | |
| SCHEMBL18851102 | 0.77 | DRD2 (0.49) | DRD2SIGMAR1 | |
| SCHEMBL13202614 | 0.74 | DRD2 (0.59) | CACNA1HDRD2MEN1KMT2AGAA | |
| SCHEMBL18233672 | 0.74 | CACNA1H (0.49) | CACNA1HDRD2MEN1KMT2AGAA | |
| SCHEMBL22754469 | 0.74 | CACNA1H (0.49) | CACNA1HDRD2MEN1KMT2AGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2079743-B1 | PTERIDINE DERIVATIVES AS POLO-LIKE KINASE INHIBITORS USEFUL IN THE TREATMENT OF CANCER | CHROMA THERAPEUTICS LTD (GB) | 2012-01-25 | — | — | EP | disclosed |