SCHEMBL376168

SCHEMBL376168

CCN(CC)CC.N#CCCC(=O)O

nearest known ligand 0.39

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
FFAR3 O14843 1/20 0.39
HDAC3 O15379 1/20 0.39
HDAC1 Q13547 1/20 0.39
HDAC2 Q92769 1/20 0.39
HDAC8 Q9BY41 1/20 0.39
PTPN7 P35236 5/20 0.37
TDP1 Q9NUW8 4/20 0.37
ALDH1A1 P00352 4/20 0.37
RECQL P46063 2/20 0.37
MEN1 O00255 2/20 0.37
KMT2A Q03164 2/20 0.37
KDM4E B2RXH2 1/20 0.37
USP2 O75604 1/20 0.37
POLB P06746 1/20 0.37
MAPT P10636 1/20 0.37
HPGD P15428 1/20 0.37
ALOX12 P18054 1/20 0.37
BLM P54132 1/20 0.37
MCL1 Q07820 1/20 0.37
SMN1; SMN2 Q16637 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Water SCHEMBL17557160 1.00 FFAR3 (0.39) FFAR3HDAC3HDAC1HDAC2HDAC8
SCHEMBL325311 0.83
Water SCHEMBL18694993 0.83
Acetic Acid SCHEMBL8800476 0.81 LMNA (0.43) FFAR3HDAC3HDAC1HDAC2HDAC8
Acetonitrile SCHEMBL29125594 0.81 LMNA (0.40) FFAR3HDAC3HDAC1HDAC2HDAC8
Hydrochloric Acid SCHEMBL11596030 0.81
Ammonia Solution, Strong SCHEMBL217276 0.81
SCHEMBL6547582 0.81 LMNA (0.44) FFAR3HDAC3HDAC1HDAC2HDAC8
Ammonia Solution, Strong SCHEMBL3713940 0.81 LMNA (0.44) FFAR3HDAC3HDAC1HDAC2HDAC8
Ammonia Solution, Strong SCHEMBL2518731 0.81 LMNA (0.44) FFAR3HDAC3HDAC1HDAC2HDAC8

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 150 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-112334776-B Hybridization of full LNA oligonucleotides 豪夫迈·罗氏有限公司 2024-07-09 CN disclosed
CN-112714649-B Cyclic dinucleotide derivatives and antibody drug conjugates thereof 第一三共株式会社 2024-07-02 CN disclosed
US-20240209432-A1 POLYPEPTIDE TAGGED NUCLEOTIDES AND USE THEREOF IN NUCLEIC ACID SEQUENCING BY NANOPORE DETECTION Roche Sequencing Solutions, Inc. (US) 2024-06-27 US disclosed
CN-114829368-B Method for sequencing by synthesis using a continuous labelling scheme 豪夫迈·罗氏有限公司 2024-06-04 CN disclosed
EP-4303314-A2 POLYPEPTIDE TAGGED NUCLEOTIDES AND USE THEREOF IN NUCLEIC ACID SEQUENCING BY NANOPORE DETECTION F. Hoffmann-La Roche AG (CH) 2024-01-10 EP disclosed
US-20230330248-A1 ANTIBODY-DRUG CONJUGATE INCLUDING NOVEL CYCLIC DINUCLEOTIDE DERIVATIVE DAIICHI SANKYO COMPANY, LIMITED (JP) 2023-10-19 US disclosed
US-11739378-B2 Polypeptide tagged nucleotides and use thereof in nucleic acid sequencing by nanopore detection Roche Sequencing Solutions, Inc. (US) 2023-08-29 US disclosed
CN-114605423-B Method for preparing alkaloids in gelsemium elegans 中国科学院大连化学物理研究所 2023-04-14 CN disclosed
EP-4115909-A1 ANTIBODY-DRUG CONJUGATE INCLUDING NOVEL CYCLIC DINUCLEOTIDE DERIVATIVE Daiichi Sankyo Company, Limited (JP) 2023-01-11 EP disclosed
CN-115209921-A Antibody drug conjugates comprising novel cyclic dinucleotide derivatives 第一三共株式会社 2022-10-18 CN disclosed
US-5449602-A Polynucleotides AMOCO CORPORATION (US) 1995-09-12 US disclosed
EP-0638089-A1 SYNTHESIS OF DIVERSE AND USEFUL COLLECTIONS OF OLIGONUCLEOTIDES THE JOHNS HOPKINS UNIVERSITY (US) 1995-02-15 EP disclosed
US-5380924-A Polymerizable emulsifiers and reactive groups and polymers of emulsifiers and other monomers BAYER AKTIENGESELLSCHAFT (DE) 1995-01-10 US disclosed
EP-0595839-A4 1994-08-03 EP disclosed
EP-0595839-A1 METHOD AND COMPOUNDS FOR RNA SYNTHESIS THE PERKIN-ELMER CORPORATION (US) 1994-05-11 EP disclosed
US-5298583-A Contains fluorescent dyestuff and protein linked to polymer BAYER AKTIENGESELLSCHAFT (DE) 1994-03-29 US disclosed
US-5281701-A Process and compounds for RNA synthesis APPLIED BIOSYSTEMS, INC. (US) 1994-01-25 US disclosed
WO-1993023570-A1 OLIGONUCLEOTIDES HAVING CONJUGATES ATTACHED AT THE 2'-POSITION OF THE SUGAR MOIETY PHARMAGENICS, INC. (US) 1993-11-25 WO disclosed
WO-1993021203-A1 SYNTHESIS OF DIVERSE AND USEFUL COLLECTIONS OF OLIGONUCLEOTIDES THE JOHNS HOPKINS UNIVERSITY (US) 1993-10-28 WO disclosed
WO-1993001204-A1 METHOD AND COMPOUNDS FOR RNA SYNTHESIS APPLIED BIOSYSTEMS, INC. (US) 1993-01-21 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11739378-B2 Polypeptide tagged nucleotides and use thereof in nucleic acid sequencing by nanopore detection NPPA, ANPEP, TENT4A FFAR3 4072/4885HDAC3 4873/4885HDAC1 4884/4885
US-20230330248-A1 ANTIBODY-DRUG CONJUGATE INCLUDING NOVEL CYCLIC DINUCLEOTIDE DERIVATIVE STING1, CGAS, TLR9 FFAR3 2093/4885HDAC3 4535/4885HDAC1 4583/4885
US-20240209432-A1 POLYPEPTIDE TAGGED NUCLEOTIDES AND USE THEREOF IN NUCLEIC ACID SEQUENCING BY NANOPORE DETECTION NPPA, ANPEP, TENT4A FFAR3 4072/4885HDAC3 4873/4885HDAC1 4884/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.