Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1635117 | 1.00 | CYP3A4 (0.45) | CYP3A4 | |
| SCHEMBL1635115 | 1.00 | CYP3A4 (0.45) | CYP3A4 | |
| SCHEMBL3761800 | 1.00 | CYP3A4 (0.45) | CYP3A4 | |
| SCHEMBL12726003 | 0.92 | CYP3A4 (0.50) | CYP3A4 | |
| SCHEMBL3756681 | 0.91 | ADORA3 (0.40) | CYP3A4 | |
| SCHEMBL3756690 | 0.91 | ADORA3 (0.40) | CYP3A4 | |
| SCHEMBL12726005 | 0.90 | — | — | |
| SCHEMBL12726004 | 0.88 | — | — | |
| SCHEMBL8117106 | 0.84 | CFD (0.43) | — | |
| SCHEMBL12765750 | 0.84 | ELANE (0.45) | CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2185524-A1 | NOVEL PEPTIDE INHIBITORS OF HEPATITIS C VIRUS REPLICATION | Intermune, Inc. (US) | 2010-05-19 | — | — | EP | disclosed |
| WO-2008141227-A1 | NOVEL PEPTIDE INHIBITORS OF HEPATITIS C VIRUS REPLICATION | INTERMUNE, INC. (US) | 2008-11-20 | — | — | WO | disclosed |