SCHEMBL3761925

SCHEMBL3761925

[CH2]Oc1ccc(Cl)c(CC)c1

nearest known ligand 0.53

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
L3MBTL1 Q9Y468 1/20 0.53
HTR2A P28223 5/20 0.49
SLC6A4 P31645 5/20 0.49
KCNH2 Q12809 5/20 0.49
KDM4E B2RXH2 4/20 0.49
ALDH1A1 P00352 2/20 0.49
GPR84 Q9NQS5 1/20 0.43
GAA P10253 1/20 0.43
P4HB P07237 1/20 0.41
NPSR1 Q6W5P4 1/20 0.41
LMNA P02545 1/20 0.39
POLB P06746 1/20 0.39
MAPT P10636 1/20 0.39
HTT P42858 1/20 0.39
SMN1; SMN2 Q16637 1/20 0.39
MCL1 Q07820 3/20 0.38
CTSD P07339 1/20 0.36
BACE1 P56817 1/20 0.36
IDO1 P14902 1/20 0.36
GRIN2D O15399 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3761927 0.82 L3MBTL1 (0.54) L3MBTL1HTR2ASLC6A4KCNH2KDM4E
SCHEMBL12126681 0.80 L3MBTL1 (0.61) L3MBTL1HTR2ASLC6A4KCNH2KDM4E
SCHEMBL5670814 0.78 L3MBTL1 (0.63) L3MBTL1HTR2ASLC6A4KCNH2KDM4E
SCHEMBL15625385 0.77 L3MBTL1 (0.71) L3MBTL1HTR2ASLC6A4KCNH2KDM4E
SCHEMBL23841500 0.76 KDM4E (0.49) L3MBTL1HTR2ASLC6A4KCNH2KDM4E
SCHEMBL994959 0.76 HTR2A (0.52) L3MBTL1HTR2ASLC6A4KCNH2KDM4E
SCHEMBL13361809 0.76 CETP (0.51) L3MBTL1HTR2ASLC6A4KCNH2KDM4E
SCHEMBL10931662 0.74 KDM4E (0.48) L3MBTL1HTR2ASLC6A4KCNH2KDM4E
SCHEMBL9486076 0.74 L3MBTL1 (0.48) L3MBTL1HTR2ASLC6A4KCNH2KDM4E
SCHEMBL13490743 0.74 L3MBTL1 (0.63) L3MBTL1HTR2ASLC6A4KCNH2KDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8426631-B2 Fungicidal compounds, method for the production thereof, and use thereof to combat damaging fungi, and agents comprising the same BASF SE (DE) 2013-04-23 US disclosed
US-20100304966-A1 Fungicidal Compounds, Method For the Production Thereof, And Use Thereof To Combat Damaging Fungi, And Agents Comprising The Same BASF SE (DE) 2010-12-02 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20100304966-A1 Fungicidal Compounds, Method For the Production Thereof, And Use Thereof To Combat Damaging Fungi, And Agents Comprising The Same CYP51A1, ERG28, CAT L3MBTL1 1100/4885HTR2A 4672/4885SLC6A4 4503/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.