Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MARK3 | P27448 | 16/20 | 0.59 |
| ▸ | SGK1 | O00141 | 3/20 | 0.57 |
| ▸ | PIK3CD | O00329 | 3/20 | 0.57 |
| ▸ | CHEK1 | O14757 | 3/20 | 0.57 |
| ▸ | MAPK13 | O15264 | 3/20 | 0.57 |
| ▸ | PDPK1 | O15530 | 3/20 | 0.57 |
| ▸ | NUAK1 | O60285 | 3/20 | 0.57 |
| ▸ | CCNT1 | O60563 | 3/20 | 0.57 |
| ▸ | JAK2 | O60674 | 3/20 | 0.57 |
| ▸ | ROCK2 | O75116 | 3/20 | 0.57 |
| ▸ | CHEK2 | O96017 | 3/20 | 0.57 |
| ▸ | EGFR | P00533 | 3/20 | 0.57 |
| ▸ | RAF1 | P04049 | 3/20 | 0.57 |
| ▸ | NTRK1 | P04629 | 3/20 | 0.57 |
| ▸ | LCK | P06239 | 3/20 | 0.57 |
| ▸ | CSF1R | P07333 | 3/20 | 0.57 |
| ▸ | MET | P08581 | 3/20 | 0.57 |
| ▸ | HCK | P08631 | 3/20 | 0.57 |
| ▸ | KIT | P10721 | 3/20 | 0.57 |
| ▸ | PIM1 | P11309 | 3/20 | 0.57 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3766935 | 0.91 | MARK3 (0.62) | MARK3SGK1PIK3CDCHEK1MAPK13 | |
| SCHEMBL3765772 | 0.83 | MARK3 (0.62) | MARK3SGK1PIK3CDCHEK1MAPK13 | |
| SCHEMBL3756874 | 0.83 | MARK3 (0.62) | MARK3SGK1PIK3CDCHEK1MAPK13 | |
| SCHEMBL3766815 | 0.81 | MARK3 (0.59) | MARK3SGK1PIK3CDCHEK1MAPK13 | |
| SCHEMBL3764411 | 0.80 | MARK3 (0.64) | MARK3SGK1PIK3CDCHEK1MAPK13 | |
| SCHEMBL3756877 | 0.80 | MARK3 (0.63) | MARK3SGK1PIK3CDCHEK1MAPK13 | |
| SCHEMBL3763607 | 0.80 | MARK3 (0.63) | MARK3SGK1PIK3CDCHEK1MAPK13 | |
| SCHEMBL3765323 | 0.80 | MARK3 (0.60) | MARK3SGK1PIK3CDCHEK1MAPK13 | |
| SCHEMBL13053471 | 0.80 | MARK3 (0.63) | MARK3SGK1PIK3CDCHEK1MAPK13 | |
| SCHEMBL12997619 | 0.79 | MARK3 (0.73) | MARK3SGK1PIK3CDCHEK1MAPK13 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 21 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11944618-B2 | Subcutaneous delivery of polymer conjugates of therapeutic agents | SERINA THERAPEUTICS, INC. (US) | 2024-04-02 | — | — | US | disclosed |
| US-20200093816-A1 | SUBCUTANEOUS DELIVERY OF POLYMER CONJUGATES OF THERAPEUTICS AGENTS | SERINA THERAPEUTICS (AL), INC. | 2020-03-26 | — | — | US | disclosed |
| EP-2773379-B1 | SUBCUTANEOUS DELIVERY OF POLYMER CONJUGATES OF THERAPEUTIC AGENTS | SERINA THERAPEUTICS INC (US) | 2019-10-09 | — | — | EP | disclosed |
| US-10426768-B2 | Subcutaneous delivery of polymer conjugates of therapeutic agents | Sarina Therapeutics, Inc. (US) | 2019-10-01 | — | — | US | disclosed |
| US-20170202972-A1 | SUBCUTANEOUS DELIVERY OF POLYMER CONJUGATES OF THERAPEUTIC AGENTS | SERINA THERAPEUTICS (AL), INC. | 2017-07-20 | — | — | US | disclosed |
| EP-2178375-B1 | PYRAZOLOÝ1,5-A¨PYRIMIDINE DERIVATIVES | MERCK SHARP & DOHME (US) | 2014-09-24 | — | — | EP | disclosed |
| EP-2178375-B1 | PYRAZOLOÝ1,5-A¨PYRIMIDINE DERIVATIVES | MERCK SHARP & DOHME (US) | 2014-09-24 | — | — | EP | disclosed |
| US-8461162-B2 | Pyrazolo[1,5-a]pyrimidine derivatives | MERCK SHARP & DOHME CORP. (US) | 2013-06-11 | — | — | US | disclosed |
| US-8461162-B2 | Pyrazolo[1,5-a]pyrimidine derivatives | MERCK SHARP & DOHME CORP. (US) | 2013-06-11 | — | — | US | disclosed |
| US-8461162-B2 | Pyrazolo[1,5-a]pyrimidine derivatives | MERCK SHARP & DOHME CORP. (US) | 2013-06-11 | — | — | US | disclosed |
| US-20100305328-A1 | PROCESS FOR PREPARATION OF PIPERIDINE CARBOXYLIC ACID | RANBAXY LABORATORIES LIMITED (IN) | 2010-12-02 | — | — | US | disclosed |
| US-20100305328-A1 | PROCESS FOR PREPARATION OF PIPERIDINE CARBOXYLIC ACID | RANBAXY LABORATORIES LIMITED (IN) | 2010-12-02 | — | — | US | disclosed |
| US-20100305091-A1 | PYRAZOLO[1,5-a]PYRIMIDINE DERIVATIVES | MERCK SHARP & DOHME LLC | 2010-12-02 | — | — | US | disclosed |
| US-20100305091-A1 | PYRAZOLO[1,5-a]PYRIMIDINE DERIVATIVES | MERCK SHARP & DOHME LLC | 2010-12-02 | — | — | US | disclosed |
| WO-2009014620-A1 | PYRAZOLO[1,5-A]PYRIMIDINE DERIVATIVES | MERCK & CO., INC. (US) | 2009-01-29 | — | — | WO | disclosed |
| US-20080269495-A1 | Process for Preparation of Piperidine Carboxylic Acid | RANBAXY LABORATORIES LIMITED (IN) | 2008-10-30 | — | — | US | disclosed |
| US-20080269495-A1 | Process for Preparation of Piperidine Carboxylic Acid | RANBAXY LABORATORIES LIMITED (IN) | 2008-10-30 | — | — | US | disclosed |
| WO-2006013550-A3 | PROCESS FOR PREPARATION OF PIPERIDINE CARBOXYLIC ACID | RANBAXY LAB LTD (IN) | 2006-04-13 | — | — | WO | disclosed |
| WO-2006013550-A2 | PROCESS FOR PREPARATION OF PIPERIDINE CARBOXYLIC ACID | RANBAXY LABORATORIES LIMITED (IN) | 2006-02-09 | — | — | WO | disclosed |
| WO-2006013550-A2 | PROCESS FOR PREPARATION OF PIPERIDINE CARBOXYLIC ACID | RANBAXY LABORATORIES LIMITED (IN) | 2006-02-09 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (7 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10426768-B2 | Subcutaneous delivery of polymer conjugates of therapeutic agents | CD44, CD47, LNPEP | MARK3 4068/4885SGK1 3292/4885PIK3CD 3476/4885 |
| US-11944618-B2 | Subcutaneous delivery of polymer conjugates of therapeutic agents | CD44, CD47, LNPEP | MARK3 3932/4885SGK1 3255/4885PIK3CD 3438/4885 |
| US-20100305091-A1 | PYRAZOLO[1,5-a]PYRIMIDINE DERIVATIVES | MAPT, TTBK1, TTBK2 | MARK3 12/4885SGK1 351/4885PIK3CD 762/4885 |
| US-20170202972-A1 | SUBCUTANEOUS DELIVERY OF POLYMER CONJUGATES OF THERAPEUTIC AGENTS | CD44, CD47, LNPEP | MARK3 4068/4885SGK1 3292/4885PIK3CD 3476/4885 |
| US-20200093816-A1 | SUBCUTANEOUS DELIVERY OF POLYMER CONJUGATES OF THERAPEUTICS AGENTS | CD44, CD47, LNPEP | MARK3 4097/4885SGK1 3228/4885PIK3CD 3657/4885 |
| US-20100305328-A1 | PROCESS FOR PREPARATION OF PIPERIDINE CARBOXYLIC ACID | OTC, DCTD, DDC | MARK3 4823/4885SGK1 3742/4885PIK3CD 770/4885 |
| US-20080269495-A1 | Process for Preparation of Piperidine Carboxylic Acid | OTC, DCTD, ODC1 | MARK3 4797/4885SGK1 3801/4885PIK3CD 497/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.