Acetonitrile

Acetonitrile

SCHEMBL3762985

CC#N.Clc1cccc(Cl)c1

nearest known ligand 0.52

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Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 3/20 0.52
TSHR P16473 3/20 0.46
KMT2A Q03164 2/20 0.42
MEN1 O00255 1/20 0.42
CYP3A4 P08684 1/20 0.42
MAPT P10636 1/20 0.42
ALOX15 P16050 1/20 0.42
SMN1; SMN2 Q16637 1/20 0.42
HSD17B10 Q99714 1/20 0.42
TDP1 Q9NUW8 1/20 0.42
CISD1 Q9NZ45 1/20 0.42
MGLL Q99685 1/20 0.41
PNMT P11086 2/20 0.41
KCNH2 Q12809 1/20 0.41
ADORA2A P29274 2/20 0.41
ADORA1 P30542 2/20 0.41
ADORA2B P29275 1/20 0.40
USP2 O75604 1/20 0.40
KDM4E B2RXH2 3/20 0.40
GAA P10253 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Acetonitrile SCHEMBL10784227 0.85 ACHE (0.55) ALDH1A1TSHRKMT2AMEN1CYP3A4
3-Chloroaniline SCHEMBL28847285 0.85 ALDH1A1 (0.77) ALDH1A1TSHRKMT2AMEN1CYP3A4
Water SCHEMBL27726908 0.85 TSHR (0.58) ALDH1A1TSHRKMT2AMEN1CYP3A4
Water SCHEMBL27888868 0.85
Acetonitrile SCHEMBL28847198 0.84 TSHR (0.74) ALDH1A1TSHRKMT2AMEN1CYP3A4
Cyanamide SCHEMBL27345527 0.83 ALDH1A1 (0.52) ALDH1A1TSHRKMT2AMEN1CYP3A4
Nitrogen SCHEMBL9794611 0.82 TSHR (0.55) ALDH1A1TSHRKMT2AMEN1CYP3A4
Chloromethane SCHEMBL27517684 0.82 TSHR (0.55) ALDH1A1TSHRTDP1MGLLPNMT
SCHEMBL28140 0.82
SCHEMBL28129975 0.82 TSHR (0.61) ALDH1A1TSHRKMT2AMEN1CYP3A4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-117603029-A Synthesis method of penconazole key intermediate 江苏禾本生化有限公司 2024-02-27 CN disclosed
CN-109613155-A A kind of detection method of armaticity nitrogenous disinfection byproducts 同济大学 2019-04-12 CN disclosed
CN-106349105-B A kind of preparation method of benzyl cyanide 河北诚信集团有限公司 2018-11-27 CN disclosed
CN-106349105-A Preparation method of substituted benzyl cyanide 河北诚信有限责任公司 2017-01-25 CN disclosed
US-8435923-B2 Compositions, materials incorporating the compositions, and methods of using the compositions and materials EMORY UNIVERSITY (US) 2013-05-07 US disclosed
US-20100305387-A1 COMPOSITIONS, MATERIALS INCORPORATING THE COMPOSITIONS, AND METHODS OF USING THE COMPOSITIONS AND MATERIALS EMORY UNIVERSITY 2010-12-02 US disclosed