SCHEMBL3763288

SCHEMBL3763288

Cc1cccc(OCCOc2ccccc2)c1C

nearest known ligand 0.59

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HTR1B P28222 1/20 0.59
PPARG P37231 6/20 0.57
PPARA Q07869 6/20 0.57
PPARD Q03181 2/20 0.57
DRD2 P14416 2/20 0.57
DRD4 P21917 1/20 0.57
HTR1A P08908 2/20 0.51
MAPT P10636 2/20 0.50
TDP1 Q9NUW8 2/20 0.50
KCNA3 P22001 2/20 0.50
HTR2A P28223 1/20 0.50
HTR7 P34969 1/20 0.50
ADRA1A P35348 1/20 0.50
HTR6 P50406 1/20 0.50
RAB9A P51151 1/20 0.50
KDM4E B2RXH2 1/20 0.50
GAA P10253 1/20 0.50
ALDH1A1 P00352 1/20 0.50
ALOX5 P09917 5/20 0.49
PTGES O14684 4/20 0.49

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5929458 0.88 HTR1B (0.71) HTR1BPPARGPPARAPPARDDRD2
SCHEMBL3762419 0.87 HTR1B (0.57) HTR1BPPARGPPARAPPARDDRD2
SCHEMBL5279270 0.86 DRD2 (0.72) HTR1BDRD2DRD4MAPTTDP1
SCHEMBL5288807 0.84 HTR1B (0.54) HTR1BPPARGPPARAPPARDDRD2
SCHEMBL15869753 0.84 L3MBTL1 (0.53) DRD2DRD4MAPTTDP1KCNA3
SCHEMBL15869663 0.82 L3MBTL1 (0.54) DRD2DRD4MAPTTDP1KCNA3
SCHEMBL5241125 0.81 HTR1B (0.62) HTR1BPPARGPPARAPPARDDRD2
SCHEMBL12301164 0.81 DRD2 (0.75) HTR1BPPARGPPARADRD2DRD4
SCHEMBL12301163 0.81 DRD2 (0.75) HTR1BPPARGPPARAPPARDDRD2
SCHEMBL20006089 0.80 HTR1B (0.53) HTR1BPPARGPPARAPPARDDRD2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8978553-B2 Heat-sensitive lithographic printing plates MITSUBISHI PAPER MILLS LIMITED (JP) 2015-03-17 US disclosed
US-20120192740-A1 FOUNTAIN SOLUTION COMPOSITION FOR LITHOGRAPHIC PRINTING PLATE AND LITHOGRAPHIC PRINTING METHOD MITSUBISHI PAPER MILLS LIMITED (JP) 2012-08-02 US disclosed
US-20100307359-A1 HEAT-SENSITIVE LITHOGRAPHIC PRINTING PLATES MITSUBISHI PAPER MILLS LIMITED (JP) 2010-12-09 US disclosed
WO-2006138653-A9 THERMAL RECORDING MATERIALS AND METHODS OF MAKING AND USING THE SAME NASHUA CORP (US) 2007-03-01 WO disclosed
US-20060293181-A1 Thermal recording materials and methods of making and using the same NASHUA CORPORATION 2006-12-28 US disclosed
WO-2006138653-A1 THERMAL RECORDING MATERIALS AND METHODS OF MAKING AND USING THE SAME NASHUA CORPORATION (US) 2006-12-28 WO disclosed
US-RE36321-E INCLUDING DIARYL DIETHER COMPOUND KANSAKI PAPER MANUFACTURING CO., LTD. (JP) 1999-09-28 US disclosed
US-4985393-A Bis/hydroxyphenylthio/ Compounds KANZAKI PAPER MANUFACTURING CO., LTD. (JP) 1991-01-15 US disclosed
EP-0373561-A2 Heat sensitive recording material KANZAKI PAPER MANUFACTURING CO., LTD. (JP) 1990-06-20 EP disclosed
EP-0141170-B1 HEAT-SENSITIVE RECORDING MATERIAL KANZAKI PAPER MANUFACTURING COMPANY LIMITED (JP) 1987-05-13 EP disclosed
US-4531140-A Heat-sensitive recording material Kansaki Paper Manufacturing Co. Ltd. (JP) 1985-07-23 US disclosed