SCHEMBL3763759

SCHEMBL3763759

Cc1ccc(OCc2cccc(COc3ccc(C)cc3C)c2)c(C)c1

nearest known ligand 0.70

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MRGPRX4 Q96LA9 8/20 0.70
FFAR4 Q5NUL3 3/20 0.57
L3MBTL1 Q9Y468 4/20 0.50
FFAR1 O14842 1/20 0.48
POLB P06746 1/20 0.48
MAOB P27338 2/20 0.47
MAPT P10636 2/20 0.47
MAPK1 P28482 2/20 0.47
TDP1 Q9NUW8 1/20 0.47
IDO1 P14902 1/20 0.47
NPC1 O15118 2/20 0.47
RAB9A P51151 2/20 0.47
SMN1; SMN2 Q16637 2/20 0.47
LMNA P02545 1/20 0.47
HPGD P15428 1/20 0.47
TSHR P16473 1/20 0.47
CASP3 P42574 1/20 0.47
SENP8 Q96LD8 1/20 0.47
SENP7 Q9BQF6 1/20 0.47
SENP6 Q9GZR1 1/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2880445 0.89 MRGPRX4 (0.66) MRGPRX4FFAR4L3MBTL1POLBMAPT
SCHEMBL12524900 0.89 MRGPRX4 (0.62) MRGPRX4FFAR4L3MBTL1MAOBMAPT
SCHEMBL2556265 0.85 MRGPRX4 (0.61) MRGPRX4FFAR4FFAR1POLB
SCHEMBL22480855 0.83 MRGPRX4 (1.00) MRGPRX4FFAR4
SCHEMBL26162605 0.82 MRGPRX4 (0.59) MRGPRX4FFAR4FFAR1POLBMAOB
SCHEMBL15701557 0.80 MRGPRX4 (0.67) MRGPRX4FFAR4MAOBIDO1
SCHEMBL8283224 0.80 FFAR4 (0.56) MRGPRX4FFAR4L3MBTL1MAOBMAPT
SCHEMBL9946034 0.79 FFAR4 (0.55) MRGPRX4FFAR4FFAR1MAOBIDO1
SCHEMBL22510481 0.77 L3MBTL1 (0.58) MRGPRX4L3MBTL1MAOBMAPTTDP1
SCHEMBL13929791 0.77 MAOB (0.59) MRGPRX4FFAR4L3MBTL1POLBMAOB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8978553-B2 Heat-sensitive lithographic printing plates MITSUBISHI PAPER MILLS LIMITED (JP) 2015-03-17 US disclosed
US-20120192740-A1 FOUNTAIN SOLUTION COMPOSITION FOR LITHOGRAPHIC PRINTING PLATE AND LITHOGRAPHIC PRINTING METHOD MITSUBISHI PAPER MILLS LIMITED (JP) 2012-08-02 US disclosed
US-20100307359-A1 HEAT-SENSITIVE LITHOGRAPHIC PRINTING PLATES MITSUBISHI PAPER MILLS LIMITED (JP) 2010-12-09 US disclosed