SCHEMBL2880445

SCHEMBL2880445

Cc1ccc(OCc2ccccc2)c(C)c1

nearest known ligand 0.66

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MRGPRX4 Q96LA9 6/20 0.66
FFAR4 Q5NUL3 2/20 0.59
L3MBTL1 Q9Y468 5/20 0.56
MAPT P10636 3/20 0.56
MAPK1 P28482 3/20 0.56
TDP1 Q9NUW8 1/20 0.56
SMN1; SMN2 Q16637 2/20 0.54
HPGD P15428 2/20 0.54
TSHR P16473 2/20 0.54
NPC1 O15118 1/20 0.54
LMNA P02545 1/20 0.54
CASP3 P42574 1/20 0.54
RAB9A P51151 1/20 0.54
SENP8 Q96LD8 1/20 0.54
SENP7 Q9BQF6 1/20 0.54
SENP6 Q9GZR1 1/20 0.54
PTGER1 P34995 1/20 0.51
PTGER4 P35408 1/20 0.51
PTGER3 P43115 1/20 0.51
PTGER2 P43116 1/20 0.51

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3763759 0.89 MRGPRX4 (0.70) MRGPRX4FFAR4L3MBTL1MAPTMAPK1
SCHEMBL686650 0.87 MAPT (0.58) MRGPRX4FFAR4L3MBTL1MAPTMAPK1
SCHEMBL9117273 0.85 HTR1A (0.55) MRGPRX4FFAR4L3MBTL1MAPTMAPK1
SCHEMBL14228414 0.85 MAPT (0.56) MRGPRX4FFAR4L3MBTL1MAPTMAPK1
SCHEMBL25081934 0.84 MAPT (0.64) MRGPRX4FFAR4L3MBTL1MAPTMAPK1
SCHEMBL1285894 0.84 FFAR4 (0.61) MRGPRX4FFAR4L3MBTL1MAPTMAPK1
SCHEMBL10176688 0.84 FFAR4 (0.57) MRGPRX4FFAR4L3MBTL1MAPTMAPK1
SCHEMBL1439758 0.84 PPARD (0.58) MRGPRX4FFAR4L3MBTL1MAPTMAPK1
SCHEMBL1615947 0.82 FFAR4 (0.56) MRGPRX4FFAR4L3MBTL1MAPTMAPK1
SCHEMBL3724105 0.82 MEN1 (0.59) FFAR4L3MBTL1MAPTMAPK1TDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 34 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7641880-B2 Room temperature synthesis of GaN nanopowder OHIO UNIVERSITY (US) 2010-01-05 US claimed
US-20070297969-A1 Room temperature synthesis of GaN nanopowder OHIO UNIVERSITY (US) 2007-12-27 US claimed
US-11858907-B2 Kinase modulators RHIZEN PHARMACEUTICALS AG (CH) 2024-01-02 US disclosed
EP-3340983-B1 ARYL, HETEROARYL, AND HETEROCYCLIC COMPOUNDS FOR TREATMENT OF IMMUNE AND INFLAMMATORY DISORDERS ACHILLION PHARMACEUTICALS INC (US) 2023-10-04 EP disclosed
US-20230151159-A1 COMPOUND FOR FORMING HARDMASK, HARDMASK COMPOSITION INCLUDING THE COMPOUND, AND METHOD OF MANUFACTURING INTEGRATED CIRCUIT DEVICE USING THE HARDMASK COMPOSITION SAMSUNG ELECTRONICS CO., LTD. (KR) 2023-05-18 US disclosed
WO-2019149260-A1 PYRIDAZINOL COMPOUND, DERIVATIVE THEREOF, PREPARATION METHOD THEREFOR, HERBICIDAL COMPOSITION AND USE THEREOF 青岛清原化合物有限公司 2019-08-08 WO disclosed
EP-3476848-A1 BENZOFURAN PYRAZOLE AMINE PROTEIN KINASE INHIBITOR Hangzhou Rex Pharmaceutical Co., Ltd (CN) 2019-05-01 EP disclosed
US-8906519-B2 Oligoaniline compounds NISSAN CHEMICAL INDUSTRIES, LTD. (JP) 2014-12-09 US disclosed
US-8895583-B2 Soluble guanylate cyclase activators MERCK SHARP & DOHME CORP. (US) 2014-11-25 US disclosed
US-20130210798-A1 SOLUBLE GUANYLATE CYCLASE ACTIVATORS MERCK SHARP & DOHME LLC 2013-08-15 US disclosed
US-8415328-B2 Factor VIIa inhibitor PHARMACYCLICS, INC (US) 2013-04-09 US disclosed
US-7482414-B2 Transition metal complex ligand and olefin polymerization catalyst containing transition metal complex SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2009-01-27 US disclosed
US-7482414-B2 Transition metal complex ligand and olefin polymerization catalyst containing transition metal complex SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2009-01-27 US disclosed
US-20080249175-A1 N-Phenyloxamide derivatives INSTITUTE OF MEDICINAL MOLECULAR DESIGN, INC. (JP) 2008-10-09 US disclosed
US-20080249175-A1 N-Phenyloxamide derivatives INSTITUTE OF MEDICINAL MOLECULAR DESIGN, INC. (JP) 2008-10-09 US disclosed
WO-2008054522-A2 ROOM TEMPERATURE SYNTHESIS OF GAN NANOPOWDER OHIO UNIVERSITY (US) 2008-05-08 WO disclosed
US-20070297969-A1 Room temperature synthesis of GaN nanopowder OHIO UNIVERSITY (US) 2007-12-27 US disclosed
US-20070135600-A1 Transition metal complex ligand and olefin polymerization catalyst containing transition metal complex SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2007-06-14 US disclosed
US-20070135600-A1 Transition metal complex ligand and olefin polymerization catalyst containing transition metal complex SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2007-06-14 US disclosed
EP-0486745-A1 Improved solvents for chromogens useful in the manufacture of carbonless copying paper MONSANTO EUROPE S.A./N.V. (BE) 1992-05-27 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20080249175-A1 N-Phenyloxamide derivatives SERPINE1, SERPINH1, F12 MRGPRX4 1448/4885FFAR4 3865/4885L3MBTL1 1734/4885
US-20070135600-A1 Transition metal complex ligand and olefin polymerization catalyst containing transition metal complex AP1M1, OR10J3, AP2M1 MRGPRX4 2675/4885FFAR4 2640/4885L3MBTL1 628/4885
US-20130210798-A1 SOLUBLE GUANYLATE CYCLASE ACTIVATORS GUCY1B1, GUCY1A1, GUCY1A2 MRGPRX4 527/4885FFAR4 732/4885L3MBTL1 3366/4885
US-11858907-B2 Kinase modulators RPS6KA1, RPS6KA2, PRKAR2A MRGPRX4 2471/4885FFAR4 3401/4885L3MBTL1 3936/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.