⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4245640 | 0.92 | HDAC4 (0.35) | — | |
| SCHEMBL10429772 | 0.79 | P2RX7 (0.33) | — | |
| SCHEMBL4521872 | 0.72 | — | — | |
| SCHEMBL335949 | 0.72 | — | — | |
| SCHEMBL14670357 | 0.72 | HDAC4 (0.33) | — | |
| SCHEMBL10429771 | 0.69 | P2RX7 (0.33) | — | |
| SCHEMBL1899256 | 0.67 | PDGFRB (0.30) | — | |
| SCHEMBL1703380 | 0.67 | PDGFRB (0.30) | — | |
| SCHEMBL1703713 | 0.67 | PDGFRB (0.30) | — | |
| SCHEMBL7125955 | 0.67 | KDM1A (0.33) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8815339-B2 | Surface modifiers and process for surface modifications of particles of metal oxide using the same | KOREA INSTITUTE OF SCIENCE AND TECHNOLOGY (KR) | 2014-08-26 | — | — | US | claimed |
| EP-2062948-B1 | Surface modifier for metal oxide particles and method for modifying surface of metal oxide particles using the same | KOREA INST SCI & TECH (KR) | 2013-10-02 | — | — | EP | claimed |
| US-7846993-B2 | conjugated diene-vinylaromatic copolymer polymerized with silica modified with an alicyclic silanetriol such as cyclopentyltrihydroxysilane, and bis(triethoxysilylpropyl)tetrasulfide or bis(triethoxysilylpropyl)disulfide; improved compatibility, dispersibility, tire wear characteristics | KOREA KUMHO PETROCHEMICAL CO., LTD. (KR) | 2010-12-07 | — | — | US | claimed |
| US-20090163633-A1 | conjugated diene-vinylaromatic copolymer polymerized with silica modified with an alicyclic silanetriol such as cyclopentyltrihydroxysilane, and bis(triethoxysilylpropyl)tetrasulfide or bis(triethoxysilylpropyl)disulfide; improved compatibility, dispersibility, tire wear characteristics | KOREA KUMHO PETROCHEMICAL CO., LTD. (KR) | 2009-06-25 | — | — | US | claimed |
| EP-2062948-A2 | Surface modifier for metal oxide particles and method for modifying surface of metal oxide particles using the same | Korea Institute of Science and Technology (KR) | 2009-05-27 | — | — | EP | claimed |
| US-20090130306-A1 | SURFACE MODIFIERS AND PROCESS FOR SURFACE MODIFICATIONS OF PARTICLES OF METAL OXIDE USING THE SAME | KOREA INSTITUTE OF SCIENCE AND TECHNLOGY (KR) | 2009-05-21 | — | — | US | claimed |
| US-8815339-B2 | Surface modifiers and process for surface modifications of particles of metal oxide using the same | KOREA INSTITUTE OF SCIENCE AND TECHNOLOGY (KR) | 2014-08-26 | — | — | US | disclosed |
| EP-2062948-B1 | Surface modifier for metal oxide particles and method for modifying surface of metal oxide particles using the same | KOREA INST SCI & TECH (KR) | 2013-10-02 | — | — | EP | disclosed |
| US-7846993-B2 | conjugated diene-vinylaromatic copolymer polymerized with silica modified with an alicyclic silanetriol such as cyclopentyltrihydroxysilane, and bis(triethoxysilylpropyl)tetrasulfide or bis(triethoxysilylpropyl)disulfide; improved compatibility, dispersibility, tire wear characteristics | KOREA KUMHO PETROCHEMICAL CO., LTD. (KR) | 2010-12-07 | — | — | US | disclosed |
| US-20090163633-A1 | conjugated diene-vinylaromatic copolymer polymerized with silica modified with an alicyclic silanetriol such as cyclopentyltrihydroxysilane, and bis(triethoxysilylpropyl)tetrasulfide or bis(triethoxysilylpropyl)disulfide; improved compatibility, dispersibility, tire wear characteristics | KOREA KUMHO PETROCHEMICAL CO., LTD. (KR) | 2009-06-25 | — | — | US | disclosed |
| EP-2062948-A2 | Surface modifier for metal oxide particles and method for modifying surface of metal oxide particles using the same | Korea Institute of Science and Technology (KR) | 2009-05-27 | — | — | EP | disclosed |
| US-20090130306-A1 | SURFACE MODIFIERS AND PROCESS FOR SURFACE MODIFICATIONS OF PARTICLES OF METAL OXIDE USING THE SAME | KOREA INSTITUTE OF SCIENCE AND TECHNLOGY (KR) | 2009-05-21 | — | — | US | disclosed |