Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | P2RX7 | Q99572 | 1/20 | 0.33 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.31 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.31 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.31 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.31 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.31 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.31 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.31 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3763968 | 0.79 | — | — | |
| SCHEMBL335949 | 0.79 | — | — | |
| SCHEMBL14670357 | 0.78 | HDAC4 (0.33) | HDAC4HDAC2HDAC8HDAC6 | |
| SCHEMBL9317155 | 0.76 | NR1H2 (0.38) | — | |
| SCHEMBL10429771 | 0.75 | P2RX7 (0.33) | P2RX7HDAC3HDAC4HDAC1HDAC7 | |
| SCHEMBL1640058 | 0.72 | KDM1A (0.32) | P2RX7HDAC4HDAC2HDAC8HDAC6 | |
| SCHEMBL4245640 | 0.72 | HDAC4 (0.35) | HDAC4HDAC2HDAC8HDAC6 | |
| SCHEMBL23532623 | 0.70 | KDM1A (0.31) | HDAC4HDAC2HDAC8HDAC6 | |
| SCHEMBL6291550 | 0.70 | KDM1A (0.31) | HDAC4HDAC2HDAC8HDAC6 | |
| SCHEMBL6294995 | 0.70 | KDM1A (0.31) | HDAC4HDAC2HDAC8HDAC6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0183382-B1 | SILICONE ELASTOMER COMPOSITION | TOSHIBA SILICONE CO., LTD. (JP) | 1990-01-03 | — | — | EP | disclosed |
| US-4657965-A | CROSSLINKED | TOSHIBA SILICONE CO., LTD. (JP) | 1987-04-14 | — | — | US | disclosed |
| EP-0183382-A1 | Silicone elastomer composition | TOSHIBA SILICONE CO., LTD. (JP) | 1986-06-04 | — | — | EP | disclosed |