SCHEMBL376450

SCHEMBL376450

CC(C)(C)OC(=O)NC(CCCCN)C(=O)O

nearest known ligand 0.53

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
FOLH1 Q04609 1/20 0.53
ITGB3 P05106 8/20 0.51
ITGA2B P08514 8/20 0.51
CTSK P43235 6/20 0.50
CTSS P25774 3/20 0.50
ALDH1A1 P00352 1/20 0.47
TSHR P16473 1/20 0.47
MEN1 O00255 1/20 0.46
GAA P10253 1/20 0.46
KMT2A Q03164 1/20 0.46
SLC6A5 Q9Y345 1/20 0.45
HDAC4 P56524 1/20 0.44
HDAC1 Q13547 1/20 0.44
HDAC6 Q9UBN7 1/20 0.44
CPB2 Q96IY4 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL47004 1.00 FOLH1 (0.53) FOLH1ITGB3ITGA2BCTSKCTSS
SCHEMBL918952 1.00 FOLH1 (0.53) FOLH1ITGB3ITGA2BCTSKCTSS
Hydrochloric Acid SCHEMBL28376761 0.98 FOLH1 (0.51) FOLH1ITGB3ITGA2BCTSKCTSS
SCHEMBL6751878 0.98 FOLH1 (0.51) FOLH1ITGB3ITGA2BCTSKCTSS
Hydrochloric Acid SCHEMBL919653 0.98 FOLH1 (0.51) FOLH1ITGB3ITGA2BCTSKCTSS
Hydrochloric Acid SCHEMBL1711148 0.98 FOLH1 (0.51) FOLH1ITGB3ITGA2BCTSKCTSS
SCHEMBL30395713 0.98 FOLH1 (0.51) FOLH1ITGB3ITGA2BCTSKCTSS
Acetic Acid SCHEMBL15812253 0.97 FOLH1 (0.50) FOLH1ITGB3ITGA2BCTSKCTSS
SCHEMBL205184 0.95 CTSK (0.51) FOLH1ITGB3ITGA2BCTSKCTSS
SCHEMBL1487792 0.95 CTSK (0.51) FOLH1ITGB3ITGA2BCTSKCTSS

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 495 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-118252820-A Dendrimer nanoparticle based on arginine polypeptide and preparation method and application thereof 南京工业大学 2024-06-28 CN claimed
CN-118005916-A Modified polyamino acid derivative with conformational regulating capability, preparation and application thereof 四川大学 2024-05-10 CN claimed
CN-115724780-B Acylthiourea compound based on hydrophobic tag, preparation method thereof and application of acylthiourea compound in resisting influenza A virus 武汉大学 2024-04-26 CN claimed
CN-115850638-A Biodegradable polyurethane elastomer, preparation method thereof and elastomer sponge with porous structure 长春赛诺海思生物医用材料有限公司 2023-03-28 CN claimed
CN-115372341-A Bioluminescence detection system of bacterial cell wall nascent peptidoglycan constructed by D-lysine derivative and application method 西北工业大学深圳研究院 2022-11-22 CN claimed
CN-111323497-B Optical purity analysis method of pasireotide starting material 武汉武药科技有限公司 2022-07-12 CN claimed
CN-110075317-B Dextran-cell-penetrating peptide polymer liposome prepared from cell-penetrating peptide modified dextran, and preparation method and application thereof 天津大学 2022-03-08 CN claimed
CN-114134141-A Chimeric phenylalanine translation system introducing unnatural amino acids and construction method thereof 浙江大学 2022-03-04 CN claimed
CN-111808278-B Branched antibacterial polyamino acid and preparation method and application thereof 中山大学 2021-12-21 CN claimed
CN-111849929-B aminoacyl-tRNA synthetase for efficiently introducing lysine derivative 苏州鲲鹏生物技术有限公司 2021-05-11 CN claimed
US-20070141663-A1 Process for the preparation of copolymer-1 DING JINGUO 2007-06-21 US claimed
WO-2007022193-A2 PROCESS FOR THE PREPARATION OF COPOLYMER-1 CHAN WAI HONG (US) 2007-02-22 WO claimed
EP-0866080-B1 Mouldings with anticoagulant properties, their preparation and their use in the manufacturing of articles useful in medical fields VESTOLIT GMBH & CO KG (DE) 2002-07-31 EP claimed
EP-0709373-B1 PYRROLIDINE DERIVATIVE ZAIDAN HOJIN BISEIBUTSU (JP) 2001-10-17 EP claimed
US-6160056-A Molding materials having anticoagulant properties, their preparation and processing to give articles which are used in medical technology VESTOLIT GMBH (DE) 2000-12-12 US claimed
CN-1265670-A Dipeptides and related compounds that inhibit VLA-4 mediated leukocyte adhesion ELAND PHARMACEUTICALS CO (US) 2000-09-06 CN claimed
EP-0866080-A2 Mouldings with anticoagulant properties, their preparation and their use in the manufacturing of articles useful in medical fields Vestolit GmbH (DE) 1998-09-23 EP claimed
EP-0861857-A2 Mouldings with anticoagulant properties, their preparation and their use in the manufacturing of articles usefull in medical fields Vestolit GmbH (DE) 1998-09-02 EP claimed
EP-0090100-B1 INSOLUBLE POLYMERS WITH ANTI-COAGULATING PROPERTIES, ARTICLES CONTAINING THEM AND METHODS OF MANUFACTURE Fougnot, Christine (FR) 1986-09-17 EP claimed
EP-0023854-B1 SOLUBLE POLYMERS POSSESSING ANTICOAGULATING PROPERTIES, PROCESS FOR PREPARING THEM AND THEIR USE AS DRUGS WITH ANTICOAGULATING ACTION Fougnot, Christine (FR) 1984-12-12 EP claimed