SCHEMBL1487792

SCHEMBL1487792

CC(C)(C)OC(=O)N[C@@H](CCCN)C(=O)O

nearest known ligand 0.51

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
CTSK P43235 8/20 0.51
CTSS P25774 4/20 0.51
MEN1 O00255 1/20 0.47
GAA P10253 1/20 0.47
KMT2A Q03164 1/20 0.47
ITGB3 P05106 7/20 0.47
ITGA2B P08514 7/20 0.47
FOLH1 Q04609 1/20 0.46
ALDH1A1 P00352 1/20 0.46
TSHR P16473 1/20 0.46
PPARA Q07869 2/20 0.44
PPARG P37231 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL205184 1.00 CTSK (0.51) CTSKCTSSMEN1GAAKMT2A
SCHEMBL205183 1.00 CTSK (0.51) CTSKCTSSMEN1GAAKMT2A
Hydrochloric Acid SCHEMBL2191093 0.98 CTSK (0.50) CTSKCTSSMEN1GAAKMT2A
Hydrochloric Acid SCHEMBL28031453 0.98 CTSK (0.50) CTSKCTSSMEN1GAAKMT2A
SCHEMBL376450 0.95 FOLH1 (0.53) CTSKCTSSMEN1GAAKMT2A
SCHEMBL47004 0.95 FOLH1 (0.53) CTSKCTSSMEN1GAAKMT2A
SCHEMBL918952 0.95 FOLH1 (0.53) CTSKCTSSMEN1GAAKMT2A
SCHEMBL30395713 0.94 FOLH1 (0.51) CTSKCTSSMEN1GAAKMT2A
Hydrochloric Acid SCHEMBL28376761 0.94 FOLH1 (0.51) CTSKCTSSMEN1GAAKMT2A
SCHEMBL6751878 0.94 FOLH1 (0.51) CTSKCTSSMEN1GAAKMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 206 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-118146569-B Hyaluronic acid-artesunate-polyarginine nanoparticle, preparation method and application 中国海洋大学 2024-11-22 CN claimed
CN-118986933-A Nanometer preparation for delivering medicine on demand aiming at inherent barrier of pancreatic cancer, and preparation method and application thereof 复旦大学 2024-11-22 CN claimed
CN-118496511-A Amphiphilic short peptide grafted hyperbranched polymer and preparation method and application thereof 同济大学 2024-08-16 CN claimed
CN-118146569-A Hyaluronic acid-artesunate-polyarginine nanoparticle, preparation method and application 中国海洋大学 2024-06-07 CN claimed
CN-115141119-A Ornithine derivative, preparation method thereof, gadobenate dimeglumine-ornithine complex, preparation and application 首都医科大学 2022-10-04 CN claimed
EP-1088020-B1 FUNCTIONALISED POLYMERS OF ALPHA-AMINO ACIDS AND THE METHOD OF PREPARATION THEREOF USTAV MAKROMOLEKULARNI CHEMIE (CZ) 2002-12-18 EP claimed
EP-4719381-A1 LIGAND-POLAR DRUG CONJUGATES Tripartite Therapeutics Inc. (TW) 2026-04-08 EP disclosed
US-20260001914-A1 MACROCYCLIC PEPTIDES TARGETING KRAS MERCK SHARP & DOHME LLC (US) 2026-01-01 US disclosed
US-20250368628-A1 METHODS AND COMPOUNDS FOR MODULATING INHERITED GENETIC DISEASES DESIGN THERAPEUTICS INC (US) 2025-12-04 US disclosed
US-12415835-B2 Peptide-compound cyclization method CHUGAI SEIYAKU KABUSHIKI KAISHA (JP) 2025-09-16 US disclosed
US-12385042-B2 Cell-penetrating peptides VECTIOPEP OÜ (EE) 2025-08-12 US disclosed
CN-120078737-A Polymer lipid hybrid nanoparticle with T cell activating capability and application thereof 厦门大学 2025-06-03 CN disclosed
EP-4558513-A1 MACROCYCLIC PEPTIDES TARGETING KRAS Merck Sharp & Dohme LLC (US) 2025-05-28 EP disclosed
WO-1999002549-A1 POLYOL-AMINO ACID COMPOUNDS HAVING ANTI-HELICOBACTER PYLORI ACTIVITY TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) 1999-01-21 WO disclosed
WO-1998038179-A1 REVERSE HYDROXAMATE DERIVATIVES AS METALLOPROTEASE INHIBITORS GLAXO GROUP LIMITED (GB) 1998-09-03 WO disclosed
US-5710324-A AMINE CONTAINING COMPOUNDS MERRELL PHARMACEUTICALS INC. (US) 1998-01-20 US disclosed
WO-1996014844-A1 CYCLIC AMIDINE ANALOGS AS INHIBITORS OF NITRIC OXIDE SYNTHASE MERCK & CO., INC. (US) 1996-05-23 WO disclosed
WO-1996001840-A1 CATIONIC LIPIDS FOR DELIVERY OF NUCLEIC ACIDS TO CELLS GILEAD SCIENCES, INC. (US) 1996-01-25 WO disclosed
US-5318992-A Administering for the treatment of hypotensive conditions and shock MERRELL DOW PHARMACEUTICALS INC. (US) 1994-06-07 US disclosed
EP-0446699-A1 Inhibitors of nitric oxide biosynthesis MERRELL PHARMACEUTICALS INC. (US) 1991-09-18 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20250368628-A1 METHODS AND COMPOUNDS FOR MODULATING INHERITED GENETIC DISEASES CLN6, GATAD2B, MITF CTSK 3830/4885CTSS 4237/4885MEN1 3157/4885
US-20260001914-A1 MACROCYCLIC PEPTIDES TARGETING KRAS KRAS, NRAS, HRAS CTSK 1467/4885CTSS 1044/4885MEN1 209/4885
US-12415835-B2 Peptide-compound cyclization method VIP, NGLY1, GLP1R CTSK 188/4885CTSS 273/4885MEN1 394/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.