Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.58 |
| ▸ | POLB | P06746 | 2/20 | 0.58 |
| ▸ | ATM | Q13315 | 1/20 | 0.48 |
| ▸ | STING1 | Q86WV6 | 1/20 | 0.45 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | IRAK4 | Q9NWZ3 | 6/20 | 0.43 |
| ▸ | NTRK1 | P04629 | 1/20 | 0.42 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.41 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15682598 | 0.86 | POLB (0.42) | LMNAPOLBIRAK4TRPV1SMN1; SMN2 | |
| SCHEMBL1259947 | 0.85 | LMNA (0.53) | LMNAPOLBATMSTING1GAA | |
| SCHEMBL12393702 | 0.85 | LMNA (0.60) | LMNAPOLBATMSTING1GAA | |
| SCHEMBL5357036 | 0.85 | LMNA (0.60) | LMNAPOLBATMSTING1GAA | |
| SCHEMBL27737488 | 0.85 | POLB (0.55) | LMNAPOLBATMSTING1GAA | |
| SCHEMBL1085471 | 0.84 | LMNA (0.57) | LMNAPOLBATMIRAK4NTRK1 | |
| SCHEMBL9262427 | 0.84 | LMNA (0.57) | LMNAPOLBATMSTING1GAA | |
| SCHEMBL3765591 | 0.84 | LMNA (0.55) | LMNAPOLBATMSTING1GAA | |
| SCHEMBL971566 | 0.84 | POLB (0.66) | LMNAPOLBATMSTING1GAA | |
| SCHEMBL973052 | 0.84 | ATM (0.69) | LMNAPOLBATMSTING1GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1771069-B1 | N-(2-(HYDROXYMETHYL) PHENYL)-1H-PYRAZOLE-4-CARBOXAMIDE DERIVATIVES AND RELATED COMPOUNDS AS MICROBICIDAL ACTIVE INGREDIENTS FOR PHYTO-PROTECTION AND THE PROTECTION OF MATERIALS | BAYER CROPSCIENCE AG (DE) | 2014-05-07 | — | — | EP | disclosed |
| EP-1771069-B1 | N-(2-(HYDROXYMETHYL) PHENYL)-1H-PYRAZOLE-4-CARBOXAMIDE DERIVATIVES AND RELATED COMPOUNDS AS MICROBICIDAL ACTIVE INGREDIENTS FOR PHYTO-PROTECTION AND THE PROTECTION OF MATERIALS | BAYER CROPSCIENCE AG (DE) | 2014-05-07 | — | — | EP | disclosed |
| US-7842710-B2 | Carboxamides | BAYER CROPSCIENCE AG (DE) | 2010-11-30 | — | — | US | disclosed |
| US-7842710-B2 | Carboxamides | BAYER CROPSCIENCE AG (DE) | 2010-11-30 | — | — | US | disclosed |
| US-7842710-B2 | Carboxamides | BAYER CROPSCIENCE AG (DE) | 2010-11-30 | — | — | US | disclosed |
| CN-1917763-B | N- (2-hydroxymethyl) phenyl-1H-pyrazole-4-carboxamide derivatives and related compounds as microbicidal active ingredients for plant protection and material protection | BAYER CROPSCIENCE AG | 2010-05-05 | — | — | CN | disclosed |
| US-20080058389-A1 | Carboxamides | BAYER INTELLECTUAL PROPERTY GMBH (DE) | 2008-03-06 | — | — | US | disclosed |
| US-20080058389-A1 | Carboxamides | BAYER INTELLECTUAL PROPERTY GMBH (DE) | 2008-03-06 | — | — | US | disclosed |
| EP-1771069-A1 | N-(2-(HYDROXYMETHYL) PHENYL)-1H-PYRAZOLE-4-CARBOXAMIDE DERIVATIVES AND RELATED COMPOUNDS AS MICROBICIDAL ACTIVE INGREDIENTS FOR PHYTO-PROTECTION AND THE PROTECTION OF MATERIALS | Bayer CropScience Aktiengesellschaft (DE) | 2007-04-11 | — | — | EP | disclosed |
| CN-1917763-A | N- (2-hydroxymethyl) phenyl-1H-pyrazole-4-carboxamide derivatives and related compounds as microbicidal active ingredients for plant protection and material protection | BAYER CROPSCIENCE AG (DE) | 2007-02-21 | — | — | CN | disclosed |
| WO-2005074686-A1 | N-(2-(HYDROXYMETHYL) PHENYL)-1H-PYRAZOLE-4-CARBOXAMIDE DERIVATIVES AND RELATED COMPOUNDS AS MICROBICIDAL ACTIVE INGREDIENTS FOR PHYTO-PROTECTION AND THE PROTECTION OF MATERIALS | BAYER CROPSCIENCE AKTIENGESELLSCHAFT (DE) | 2005-08-18 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080058389-A1 | Carboxamides | CBR3, CBR1, H1-10 | LMNA 3877/4885POLB 4259/4885ATM 3443/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.