Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ATM | Q13315 | 1/20 | 0.69 |
| ▸ | LMNA | P02545 | 2/20 | 0.59 |
| ▸ | POLB | P06746 | 1/20 | 0.59 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.50 |
| ▸ | STING1 | Q86WV6 | 1/20 | 0.45 |
| ▸ | GAA | P10253 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.45 |
| ▸ | PDK1 | Q15118 | 1/20 | 0.45 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.45 |
| ▸ | PDK3 | Q15120 | 1/20 | 0.45 |
| ▸ | PDK4 | Q16654 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | IRAK4 | Q9NWZ3 | 2/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.43 |
| ▸ | BACE1 | P56817 | 1/20 | 0.42 |
| ▸ | BACE2 | Q9Y5Z0 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5357036 | 0.86 | LMNA (0.60) | ATMLMNAPOLBSTING1GAA | |
| SCHEMBL12393702 | 0.86 | LMNA (0.60) | ATMLMNAPOLBSTING1GAA | |
| SCHEMBL971566 | 0.85 | POLB (0.66) | ATMLMNAPOLBSMN1; SMN2STING1 | |
| SCHEMBL973582 | 0.84 | LMNA (0.56) | ATMLMNAPOLBSMN1; SMN2STING1 | |
| SCHEMBL3764560 | 0.84 | LMNA (0.58) | ATMLMNAPOLBSMN1; SMN2STING1 | |
| SCHEMBL21652207 | 0.84 | LMNA (0.58) | ATMLMNAPOLBSMN1; SMN2STING1 | |
| SCHEMBL9262427 | 0.83 | LMNA (0.57) | ATMLMNAPOLBSTING1GAA | |
| SCHEMBL1085471 | 0.83 | LMNA (0.57) | ATMLMNAPOLBMAPTIRAK4 | |
| SCHEMBL122740 | 0.82 | LMNA (0.56) | ATMLMNAPOLBSMN1; SMN2STING1 | |
| SCHEMBL973104 | 0.82 | LMNA (0.56) | ATMLMNAPOLBSTING1GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2257530-B1 | PROCESS FOR PREPARING SUBSTITUTED BIPHENYLANILIDES | BAYER CROPSCIENCE AG (DE) | 2011-10-12 | — | — | EP | disclosed |
| US-20110003999-A1 | Process for Preparing Substituted Biphenylanilides | BAYER CROPSCIENCE AG (DE) | 2011-01-06 | — | — | US | disclosed |
| EP-2093216-A1 | Process for preparing substituted biphenylanilides | Bayer CropScience AG (DE) | 2009-08-26 | — | — | EP | disclosed |
| US-7173055-B1 | Pyrazolecarboxamide and pyrazolethioamide as fungicide | SYNGENTA CROP PROTECTION, INC. (US) | 2007-02-06 | — | — | US | disclosed |
| EP-1235811-B1 | PYRAZOLECARBOXAMIDE AND PYRAZOLETHIOAMIDE AS FUNGICIDE | SYNGENTA PARTICIPATIONS AG (CH) | 2005-06-01 | — | — | EP | disclosed |
| EP-1235811-A1 | PYRAZOLECARBOXAMIDE AND PYRAZOLETHIOAMIDE AS FUNGICIDE | Syngenta Participations AG (CH) | 2002-09-04 | — | — | EP | disclosed |
| WO-2001042223-A1 | PYRAZOLECARBOXAMIDE AND PYRAZOLETHIOAMIDE AS FUNGICIDE | SYNGENTA PARTICIPATIONS AG (CH) | 2001-06-14 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110003999-A1 | Process for Preparing Substituted Biphenylanilides | DDT, PAH, THOP1 | ATM 3682/4885LMNA 3959/4885POLB 425/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.