SCHEMBL3764832

SCHEMBL3764832

C/C=C/CCOc1cccc(NC)c1F

nearest known ligand 0.33

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
APP P05067 1/20 0.33
HTR1B P28222 2/20 0.33
HTR1D P28221 1/20 0.32
NCF1 P14598 1/20 0.31
SLC6A4 P31645 2/20 0.31
HRH1 P35367 1/20 0.31
PTPN1 P18031 1/20 0.31
L3MBTL1 Q9Y468 3/20 0.31
ALDH1A1 P00352 1/20 0.31
MAPT P10636 1/20 0.31
MAPK1 P28482 1/20 0.31
TDP1 Q9NUW8 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3659827 1.00 APP (0.33) APPHTR1BHTR1DNCF1SLC6A4
SCHEMBL3770862 0.93 L3MBTL1 (0.36) APPHTR1BHTR1DNCF1SLC6A4
SCHEMBL3663647 0.93 L3MBTL1 (0.36) APPHTR1BHTR1DNCF1SLC6A4
SCHEMBL3766276 0.92 LTB4R (0.36) APPHTR1BHTR1DSLC6A4HRH1
SCHEMBL3664801 0.92 LTB4R (0.36) APPHTR1BHTR1DSLC6A4HRH1
SCHEMBL3770670 0.90 LTB4R (0.35) APPHTR1BSLC6A4HRH1PTPN1
SCHEMBL3661518 0.90 LTB4R (0.35) APPHTR1BSLC6A4HRH1PTPN1
SCHEMBL3660391 0.87 PTPN1 (0.35) APPHTR1BHTR1DNCF1SLC6A4
SCHEMBL3772711 0.87 EDNRA (0.33) APPHTR1BHTR1DNCF1SLC6A4
SCHEMBL3766152 0.87 PTPN1 (0.35) APPHTR1BHTR1DNCF1SLC6A4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20100311790-A1 AMIDE COMPOUNDS AND PLANT DISEASE CONTROLLING METHOD USING SAME SUMITOMO CHIEMCAL COMPANY LIMITED (JP) 2010-12-09 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20100311790-A1 AMIDE COMPOUNDS AND PLANT DISEASE CONTROLLING METHOD USING SAME ATL3, NAT1, C5 APP 2380/4885HTR1B 2458/4885HTR1D 2572/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.