Known targets — ChEMBL curated mechanism
ACHEBDKRB2CHRM1CHRM2CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNGGUCY1A1GUCY1A2GUCY1B1GUCY1B2NAMPTPTAFRSLC10A2SLC6A2SLC6A3TACR1dacAdacBdacCftsImrcAmrcBmrdA
The experimentally established mechanism targets of Hydrochloric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM2 known ✓ | P08172 | 1/20 | 0.34 |
| ▸ | CHRM1 known ✓ | P11229 | 1/20 | 0.34 |
| ▸ | CHRM3 known ✓ | P20309 | 1/20 | 0.34 |
| ▸ | SLC6A2 known ✓ | P23975 | 1/20 | 0.34 |
| ▸ | SLC6A3 known ✓ | Q01959 | 1/20 | 0.34 |
| ▸ | HTR2A | P28223 | 2/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | TP53 | P04637 | 1/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.34 |
| ▸ | DRD2 | P14416 | 1/20 | 0.34 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.34 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.34 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.34 |
| ▸ | HTR2C | P28335 | 1/20 | 0.34 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.34 |
| ▸ | HRH1 | P35367 | 1/20 | 0.34 |
| ▸ | DRD3 | P35462 | 1/20 | 0.34 |
| ▸ | THPO | P40225 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL966189 | 1.00 | HTR2A (0.37) | HTR2AKDM4ELMNATP53CHRM2 | |
| Hydrochloric Acid SCHEMBL29407230 | 1.00 | HTR2A (0.37) | HTR2AKDM4ELMNATP53CHRM2 | |
| Hydrochloric Acid SCHEMBL7766818 | 0.98 | HTR2A (0.36) | HTR2AKDM4ELMNATP53CHRM2 | |
| Bromide SCHEMBL6908307 | 0.96 | HTR2A (0.41) | HTR2AKDM4ELMNATP53CHRM2 | |
| SCHEMBL8357749 | 0.93 | HTR2A (0.35) | HTR2AKDM4ELMNATP53CHRM2 | |
| Phenol SCHEMBL3773251 | 0.89 | SIGMAR1 (0.33) | HTR2AKDM4ELMNATP53CHRM2 | |
| Hydrochloric Acid SCHEMBL6904826 | 0.87 | HTR2A (0.33) | HTR2AKDM4ELMNATP53CHRM2 | |
| Hydrochloric Acid SCHEMBL7636014 | 0.83 | — | — | |
| Hydrochloric Acid SCHEMBL30661096 | 0.83 | HTR2A (0.33) | HTR2AKDM4ELMNATP53CHRM2 | |
| Hydrochloric Acid SCHEMBL618390 | 0.83 | HTR2A (0.33) | HTR2AKDM4ELMNATP53CHRM2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 577 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-12187835-B2 | Process for preparing a catalyst for olefin polymerization | Hanwha Solutions Corporation (KR) | 2025-01-07 | — | — | US | disclosed |
| EP-3878871-B1 | METHOD FOR PREPARING OLEFIN POLYMERIZATION CATALYST | HANWHA SOLUTIONS CORP (KR) | 2024-08-07 | — | — | EP | disclosed |
| US-20230174758-A1 | POLYPROPYLENE-BASED RESIN COMPOSITION, LAMINATE, AND METHODS FOR PRODUCING THEM | JAPAN POLYPROPYLENE CORPORATION (JP) | 2023-06-08 | — | — | US | disclosed |
| US-11643533-B2 | Film, method of producing film, and bag | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2023-05-09 | — | — | US | disclosed |
| US-11643485-B2 | Ethylene-based polymer, polyethylene-based resin composition and use thereof, catalyst component for olefin polymerization, olefin polymerization catalyst containing the component, and method for producing ethylene-based polymer by using the catalyst | JAPAN POLYETHYLENE CORPORATION (JP) | 2023-05-09 | — | — | US | disclosed |
| EP-4159439-A1 | POLYPROPYLENE-BASED RESIN COMPOSITION, LAMINATE, AND METHODS FOR PRODUCING THESE | Japan Polypropylene Corporation (JP) | 2023-04-05 | — | — | EP | disclosed |
| WO-2022250456-A1 | HIGH-VOLTAGE CABLE MATERIAL AND MANUFACTURING METHOD THEREFOR | 한국생산기술연구원 | 2022-12-01 | — | — | WO | disclosed |
| US-11472899-B2 | Ethylene-α-olefin copolymer, method of producing ethylene-α-olefin copolymer, ethylene-based resin composition, and film | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2022-10-18 | — | — | US | disclosed |
| US-11352448-B2 | Method of transferring slurry, method of producing polyolefin, and use thereof | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2022-06-07 | — | — | US | disclosed |
| EP-3660133-B1 | POLYALPHAOLEFIN HAVING UNIFORM STRUCTURE AND METHOD OF PREPARING SAME | DL CHEMICAL CO LTD (KR) | 2022-03-23 | — | — | EP | disclosed |
| US-5145818-A | OLEFIN POLYMERIZATION CATALYST AND PROCESS FOR THE POLYMERIZATION OF OLEFINS | MITSUI PETROCHEMICAL INDUSTRIES, LTD. (JP) | 1992-09-08 | — | — | US | disclosed |
| EP-0498675-A2 | Production of alpha-olefin polymers | MITSUBISHI CHEMICAL CORPORATION (JP) | 1992-08-12 | — | — | EP | disclosed |
| US-5120696-A | OLEFIN POLYMERIZATION CATALYST AND PROCESS FOR THE POLYMERIZATION OF OLEFINS | MITSUI PETROCHEMICAL INDUSTRIES, LTD. (JP) | 1992-06-09 | — | — | US | disclosed |
| EP-0487278-A2 | Functionalized olefin polymers | MITSUBISHI CHEMICAL CORPORATION (JP) | 1992-05-27 | — | — | EP | disclosed |
| EP-0478800-A1 | HOT-MELT ADHESIVE | MITSUI PETROCHEMICAL INDUSTRIES, LTD. (JP) | 1992-04-08 | — | — | EP | disclosed |
| EP-0452920-A2 | Process for the preparation of an ethylene copolymer and an olefin polymer, and catalysts for olefin polymerization | MITSUI PETROCHEMICAL INDUSTRIES, LTD. (JP) | 1991-10-23 | — | — | EP | disclosed |
| EP-0447035-A2 | Method for the preparation of ethylene polymer compositions | MITSUI PETROCHEMICAL INDUSTRIES, LTD. (JP) | 1991-09-18 | — | — | EP | disclosed |
| EP-0442725-A2 | Olefin polymerization solid catalysts and process for the polymerization of olefins | MITSUI PETROCHEMICAL INDUSTRIES, LTD. (JP) | 1991-08-21 | — | — | EP | disclosed |
| EP-0439964-A2 | Olefin polymerization catalyst and process for the polymerization of olefins | MITSUI PETROCHEMICAL INDUSTRIES, LTD. (JP) | 1991-08-07 | — | — | EP | disclosed |
| EP-0436399-A2 | Olefin polymerization catalyst and process for the polymerization of olefins | MITSUI PETROCHEMICAL INDUSTRIES, LTD. (JP) | 1991-07-10 | — | — | EP | disclosed |