SCHEMBL376490

SCHEMBL376490

C[Si](C)=[Zr](Cl)(Cl)(C1C=Cc2ccccc21)C1C=Cc2ccccc21

nearest known ligand 0.36

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HTR2A P28223 2/20 0.36
HTR6 P50406 1/20 0.36
KDM4E B2RXH2 2/20 0.33
LMNA P02545 1/20 0.33
TP53 P04637 1/20 0.33
CHRM2 P08172 1/20 0.33
CYP3A4 P08684 1/20 0.33
CYP2D6 P10635 1/20 0.33
CHRM1 P11229 1/20 0.33
DRD2 P14416 1/20 0.33
ADRA2B P18089 1/20 0.33
ADRA2C P18825 1/20 0.33
NFKB1 P19838 1/20 0.33
CHRM3 P20309 1/20 0.33
SLC6A2 P23975 1/20 0.33
HTR2C P28335 1/20 0.33
ADRA1A P35348 1/20 0.33
HRH1 P35367 1/20 0.33
DRD3 P35462 1/20 0.33
THPO P40225 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7935566 0.88 SLC22A2 (0.33) HTR2AHTR6KDM4ELMNATP53
SCHEMBL19517753 0.86 HTR6 (0.33) HTR2AHTR6
SCHEMBL1538971 0.84 HTR2A (0.35) HTR2AHTR6KDM4ELMNATP53
SCHEMBL7636017 0.84
SCHEMBL618391 0.83 HTR6 (0.33) HTR2AHTR6KDM4ELMNATP53
SCHEMBL7642384 0.83 RET (0.36) HTR2AHTR6KDM4ELMNATP53
SCHEMBL7641858 0.82 HTR6 (0.31) HTR2AHTR6
SCHEMBL7641966 0.82
SCHEMBL7643746 0.81 HTR2A (0.37) HTR2AHTR6KDM4ELMNATP53
SCHEMBL8426880 0.81 HTR2C (0.32) HTR2C

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 633 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20240076422-A1 SUPPORTED METALLOCENE CATALYST, METHOD FOR PREPARING THE SAME, AND USE OF THE SAME FOR PREPARING POLYOLEFIN NATIONAL CHUNG CHENG UNIVERSITY (TW) 2024-03-07 US claimed
EP-3893054-B1 PATTERN FORMING METHOD, PHOTOSENSITIVE RESIN COMPOSITION, CURED FILM, LAMINATE, AND DEVICE FUJIFILM CORP (JP) 2026-05-06 EP disclosed
US-12393116-B2 Pattern forming method, photosensitive resin composition, cured film, laminate, and device FUJIFILM CORPORATION (JP) 2025-08-19 US disclosed
EP-3893053-B1 PHOTOSENSITIVE RESIN COMPOSITION, PATTERN FORMING METHOD, CURED FILM, MULTILAYER BODY AND DEVICE FUJIFILM CORP (JP) 2025-01-22 EP disclosed
US-12187835-B2 Process for preparing a catalyst for olefin polymerization Hanwha Solutions Corporation (KR) 2025-01-07 US disclosed
US-12078929-B2 Photosensitive resin composition, pattern forming method, cured film, laminate, and device FUJIFILM CORPORATION (JP) 2024-09-03 US disclosed
EP-3878871-B1 METHOD FOR PREPARING OLEFIN POLYMERIZATION CATALYST HANWHA SOLUTIONS CORP (KR) 2024-08-07 EP disclosed
US-20240076422-A1 SUPPORTED METALLOCENE CATALYST, METHOD FOR PREPARING THE SAME, AND USE OF THE SAME FOR PREPARING POLYOLEFIN NATIONAL CHUNG CHENG UNIVERSITY (TW) 2024-03-07 US disclosed
US-20230174758-A1 POLYPROPYLENE-BASED RESIN COMPOSITION, LAMINATE, AND METHODS FOR PRODUCING THEM JAPAN POLYPROPYLENE CORPORATION (JP) 2023-06-08 US disclosed
US-11643533-B2 Film, method of producing film, and bag SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2023-05-09 US disclosed
US-5145818-A OLEFIN POLYMERIZATION CATALYST AND PROCESS FOR THE POLYMERIZATION OF OLEFINS MITSUI PETROCHEMICAL INDUSTRIES, LTD. (JP) 1992-09-08 US disclosed
EP-0498675-A2 Production of alpha-olefin polymers MITSUBISHI CHEMICAL CORPORATION (JP) 1992-08-12 EP disclosed
US-5120696-A OLEFIN POLYMERIZATION CATALYST AND PROCESS FOR THE POLYMERIZATION OF OLEFINS MITSUI PETROCHEMICAL INDUSTRIES, LTD. (JP) 1992-06-09 US disclosed
EP-0487278-A2 Functionalized olefin polymers MITSUBISHI CHEMICAL CORPORATION (JP) 1992-05-27 EP disclosed
EP-0478800-A1 HOT-MELT ADHESIVE MITSUI PETROCHEMICAL INDUSTRIES, LTD. (JP) 1992-04-08 EP disclosed
EP-0452920-A2 Process for the preparation of an ethylene copolymer and an olefin polymer, and catalysts for olefin polymerization MITSUI PETROCHEMICAL INDUSTRIES, LTD. (JP) 1991-10-23 EP disclosed
EP-0447035-A2 Method for the preparation of ethylene polymer compositions MITSUI PETROCHEMICAL INDUSTRIES, LTD. (JP) 1991-09-18 EP disclosed
EP-0442725-A2 Olefin polymerization solid catalysts and process for the polymerization of olefins MITSUI PETROCHEMICAL INDUSTRIES, LTD. (JP) 1991-08-21 EP disclosed
EP-0439964-A2 Olefin polymerization catalyst and process for the polymerization of olefins MITSUI PETROCHEMICAL INDUSTRIES, LTD. (JP) 1991-08-07 EP disclosed
EP-0436399-A2 Olefin polymerization catalyst and process for the polymerization of olefins MITSUI PETROCHEMICAL INDUSTRIES, LTD. (JP) 1991-07-10 EP disclosed