SCHEMBL618391

SCHEMBL618391

C[Si](c1ccccc1)=[Zr](Cl)(Cl)(C1C=Cc2ccccc21)C1C=Cc2ccccc21

nearest known ligand 0.33

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HTR6 P50406 1/20 0.33
HTR2A P28223 2/20 0.33
SIGMAR1 Q99720 2/20 0.31
KDM4E B2RXH2 1/20 0.30
LMNA P02545 1/20 0.30
TP53 P04637 1/20 0.30
CHRM2 P08172 1/20 0.30
CYP3A4 P08684 1/20 0.30
CYP2D6 P10635 1/20 0.30
CHRM1 P11229 1/20 0.30
DRD2 P14416 1/20 0.30
ADRA2B P18089 1/20 0.30
ADRA2C P18825 1/20 0.30
NFKB1 P19838 1/20 0.30
CHRM3 P20309 1/20 0.30
SLC6A2 P23975 1/20 0.30
HTR2C P28335 1/20 0.30
ADRA1A P35348 1/20 0.30
HRH1 P35367 1/20 0.30
DRD3 P35462 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL547453 0.84 HTR2A (0.34) HTR6HTR2A
SCHEMBL376490 0.83 HTR2A (0.36) HTR6HTR2ASIGMAR1KDM4ELMNA
SCHEMBL8676857 0.81 HTR2A (0.33) HTR6HTR2ASIGMAR1KDM4ELMNA
SCHEMBL7642384 0.78 RET (0.36) HTR6HTR2ASIGMAR1KDM4ELMNA
SCHEMBL7643746 0.76 HTR2A (0.37) HTR6HTR2ASIGMAR1KDM4ELMNA
SCHEMBL7935566 0.76 SLC22A2 (0.33) HTR6HTR2AKDM4ELMNATP53
SCHEMBL1538971 0.76 HTR2A (0.35) HTR6HTR2ASIGMAR1KDM4ELMNA
SCHEMBL19517753 0.75 HTR6 (0.33) HTR6HTR2A
SCHEMBL3380394 0.74 HTR2A (0.35) HTR6HTR2ASIGMAR1KDM4ELMNA
SCHEMBL1625095 0.74 HTR2A (0.34) HTR6HTR2ASIGMAR1KDM4ELMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 253 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10870715-B2 Solid polyaluminoxane composition, olefin polymerization catalyst, olefin polymer production method and solid polyaluminoxane composition production method MITSUI CHEMICALS, INC. (JP) 2020-12-22 US disclosed
EP-3312200-B1 SOLID POLYALUMINOXANE COMPOSITION, OLEFIN POLYMERIZATION CATALYST, OLEFIN POLYMER PRODUCTION METHOD AND SOLID POLYALUMINOXANE COMPOSITION PRODUCTION METHOD MITSUI CHEMICALS INC (JP) 2019-06-19 EP disclosed
US-10150823-B2 Solid polyaluminoxane composition, olefin polymerization catalyst, olefin polymer production method and solid polyaluminoxane composition production method MITSUI CHEMICALS, INC. (JP) 2018-12-11 US disclosed
US-10087262-B2 Ethylene polymer, stretch-molded product obtained by stretching the same, and method for producing ethylene polymer ASAHI KASEI KABUSHIKI KAISHA (JP) 2018-10-02 US disclosed
EP-3312200-A1 SOLID POLYALUMINOXANE COMPOSITION, OLEFIN POLYMERIZATION CATALYST, OLEFIN POLYMER PRODUCTION METHOD AND SOLID POLYALUMINOXANE COMPOSITION PRODUCTION METHOD Mitsui Chemicals, Inc. (JP) 2018-04-25 EP disclosed
EP-2955187-B1 SOLID POLYALUMINOXANE COMPOSITION, CATALYST FOR OLEFIN POLYMERIZATION AND METHOD FOR PRODUCING OLEFIN POLYMER MITSUI CHEMICALS INC (JP) 2018-01-31 EP disclosed
US-20170298156-A1 ETHYLENE POLYMER, STRETCH-MOLDED PRODUCT OBTAINED BY STRETCHING THE SAME, AND METHOD FOR PRODUCING ETHYLENE POLYMER ASAHI KASEI KABUSHIKI KAISHA (JP) 2017-10-19 US disclosed
US-20170240664-A1 SOLID POLYALUMINOXANE COMPOSITION, OLEFIN POLYMERIZATION CATALYST, OLEFIN POLYMER PRODUCTION METHOD AND SOLID POLYALUMINOXANE COMPOSITION PRODUCTION METHOD MITSUI CHEMICALS, INC. (JP) 2017-08-24 US disclosed
US-9676879-B2 Solid polyaluminoxane composition, olefin polymerization catalyst, olefin polymer production method and solid polyaluminoxane composition production method MITSUI CHEMICALS, INC. (JP) 2017-06-13 US disclosed
EP-1348721-B2 Process for producing polyolefin MITSUI CHEMICALS INC (JP) 2017-05-10 EP disclosed
US-5292845-A Ethylene/alpha-olefin/7-methyl-1,6-octadiene copolymer rubber and composition of the same MITSUI PETROCHEMICAL INDUSTRIES, LTD. (JP) 1994-03-08 US disclosed
EP-0582480-A2 Olefin polymerization catalyst and method for the polymerization of olefin using said polymerization catalyst MITSUI PETROCHEMICAL INDUSTRIES, LTD. (JP) 1994-02-09 EP disclosed
EP-0575123-A2 Ethylene copolymer composition MITSUI PETROCHEMICAL INDUSTRIES, LTD. (JP) 1993-12-22 EP disclosed
US-5252529-A Coordination catalyst using a moisture-adsorbed carrier of a metal oxide; addition polymers having excellent melt tension and moldability and broad molecular weight distribution MITSUI PETROCHEMICAL INDUSTRIES, LTD. (JP) 1993-10-12 US disclosed
EP-0552946-A1 Ethylene/alpha-olefin/7-methyl-1,6-octadiene copolymer rubber and composition of the same MITSUI PETROCHEMICAL INDUSTRIES, LTD. (JP) 1993-07-28 EP disclosed
EP-0552945-A2 Process for the preparation of polyolefin MITSUI PETROCHEMICAL INDUSTRIES, LTD. (JP) 1993-07-28 EP disclosed
EP-0536503-A2 Olefin polymer composition MITSUI PETROCHEMICAL INDUSTRIES, LTD. (JP) 1993-04-14 EP disclosed
EP-0534119-A2 Prepolymerized olefin polymerization catalyst and olefin polymerization process MITSUI PETROCHEMICAL INDUSTRIES, LTD. (JP) 1993-03-31 EP disclosed
EP-0516458-A2 Olefin polymerization solid catalyst, olefin polymerization catalyst and olefin polymerization MITSUI PETROCHEMICAL INDUSTRIES, LTD. (JP) 1992-12-02 EP disclosed
EP-0515132-A2 Olefin polymerization catalyst and olefin polymerization MITSUI PETROCHEMICAL INDUSTRIES, LTD. (JP) 1992-11-25 EP disclosed