Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH1 | P35367 | 2/20 | 0.50 |
| ▸ | HTR2A | P28223 | 2/20 | 0.50 |
| ▸ | SLC7A5 | Q01650 | 7/20 | 0.44 |
| ▸ | TAAR1 | Q96RJ0 | 4/20 | 0.42 |
| ▸ | KIF11 | P52732 | 1/20 | 0.39 |
| ▸ | MAOA | P21397 | 1/20 | 0.38 |
| ▸ | CSNK1E | P49674 | 1/20 | 0.37 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.37 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27565319 | 0.86 | CSNK1E (0.51) | HTR2ACSNK1E | |
| SCHEMBL11092760 | 0.84 | HRH1 (0.52) | HRH1HTR2ASLC7A5TAAR1KIF11 | |
| SCHEMBL11474474 | 0.84 | CSNK1E (0.49) | HRH1HTR2ATAAR1CSNK1EADRA2A | |
| SCHEMBL9846073 | 0.81 | POLB (0.45) | HRH1HTR2ATAAR1CSNK1EADRA2A | |
| SCHEMBL28004004 | 0.79 | HRH1 (0.55) | HRH1HTR2ASLC7A5TAAR1MAOA | |
| SCHEMBL14459040 | 0.79 | TAAR1 (0.57) | HRH1HTR2ASLC7A5TAAR1MAOA | |
| SCHEMBL8003693 | 0.79 | HRH1 (0.55) | HRH1HTR2ASLC7A5TAAR1MAOA | |
| SCHEMBL26720658 | 0.77 | SLC7A5 (0.50) | HRH1HTR2ASLC7A5TAAR1KIF11 | |
| SCHEMBL14387157 | 0.77 | TAAR1 (0.59) | HRH1HTR2ASLC7A5TAAR1MAOA | |
| SCHEMBL8829324 | 0.77 | HRH1 (0.57) | HRH1HTR2ASLC7A5TAAR1MAOA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7851530-B2 | High viscosity at low shear; for use as sag control agents in coatings, paints, cosmetics, mining, paper, textile industries; Urea reaction product of isocyanate such as hexamethylene diisocyanate with high enantiomeric excess of optically active methylamines such as alpha-methylbenzylamine | NUPLEX RESINS B.V. (NL) | 2010-12-14 | — | — | US | disclosed |
| US-20060289828-A1 | Carbon-substituted methyl amine derivatives and their use as a rheology control agents | ALLNEX NETHERLANDS B.V. (NL) | 2006-12-28 | — | — | US | disclosed |