SCHEMBL26720658

SCHEMBL26720658

CC[C@@H](CCCCN)[C@H](C)c1ccccc1

nearest known ligand 0.50

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
SLC7A5 Q01650 7/20 0.50
HRH1 P35367 2/20 0.48
HTR2A P28223 2/20 0.48
TAAR1 Q96RJ0 4/20 0.41
SIGMAR1 Q99720 1/20 0.39
KIF11 P52732 1/20 0.38
LMNA P02545 1/20 0.37
MAOA P21397 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29002686 0.80 TAAR1 (0.54) HRH1HTR2ATAAR1LMNA
SCHEMBL11092760 0.79 HRH1 (0.52) SLC7A5HRH1HTR2ATAAR1SIGMAR1
SCHEMBL3765092 0.77 HRH1 (0.50) SLC7A5HRH1HTR2ATAAR1KIF11
SCHEMBL18863924 0.77 LMNA (0.41) HRH1HTR2ATAAR1LMNA
SCHEMBL9846077 0.77 TAAR1 (0.50) HRH1HTR2ATAAR1LMNA
SCHEMBL14387157 0.76 TAAR1 (0.59) SLC7A5HRH1HTR2ATAAR1MAOA
SCHEMBL3428511 0.76 TAAR1 (0.59) SLC7A5HRH1HTR2ATAAR1MAOA
Benzene SCHEMBL27904738 0.75 HTR2A (0.52) SLC7A5HRH1HTR2ATAAR1SIGMAR1
SCHEMBL335854 0.74 LMNA (0.42) HRH1HTR2ATAAR1LMNA
SCHEMBL14459040 0.74 TAAR1 (0.57) SLC7A5HRH1HTR2ATAAR1MAOA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230348524-A1 TECHNOLOGIES FOR OLIGONUCLEOTIDE PREPARATION WAVE LIFE SCIENCES LTD. (SG) 2023-11-02 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230348524-A1 TECHNOLOGIES FOR OLIGONUCLEOTIDE PREPARATION POLRMT, DCLRE1B, RNGTT SLC7A5 4096/4885HRH1 4875/4885HTR2A 4170/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.