Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABCC9 | O60706 | 1/20 | 0.88 |
| ▸ | ABCC8 | Q09428 | 1/20 | 0.88 |
| ▸ | KCNJ11 | Q14654 | 1/20 | 0.88 |
| ▸ | NLRP3 | Q96P20 | 3/20 | 0.56 |
| ▸ | DNMT3A | Q9Y6K1 | 1/20 | 0.52 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.48 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.48 |
| ▸ | GAA | P10253 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Clamikalant SCHEMBL29387853 | 0.94 | ABCC9 (1.00) | ABCC9ABCC8KCNJ11NLRP3DNMT3A | |
| Clamikalant SCHEMBL726268 | 0.94 | ABCC9 (1.00) | ABCC9ABCC8KCNJ11NLRP3DNMT3A | |
| Clamikalant SCHEMBL4254889 | 0.93 | ABCC9 (0.98) | ABCC9ABCC8KCNJ11NLRP3DNMT3A | |
| Clamikalant SCHEMBL4254888 | 0.93 | ABCC9 (0.98) | ABCC9ABCC8KCNJ11NLRP3DNMT3A | |
| SCHEMBL726272 | 0.87 | ABCC9 (0.87) | ABCC9ABCC8KCNJ11NLRP3DNMT3A | |
| SCHEMBL6567784 | 0.86 | ABCC9 (0.85) | ABCC9ABCC8KCNJ11NLRP3DNMT3A | |
| SCHEMBL6567790 | 0.86 | ABCC9 (0.85) | ABCC9ABCC8KCNJ11NLRP3DNMT3A | |
| SCHEMBL7016981 | 0.86 | ABCC9 (0.85) | ABCC9ABCC8KCNJ11NLRP3DNMT3A | |
| SCHEMBL7018854 | 0.84 | ABCC9 (0.82) | ABCC9ABCC8KCNJ11NLRP3DNMT3A | |
| SCHEMBL4261594 | 0.84 | ABCC9 (0.82) | ABCC9ABCC8KCNJ11NLRP3DNMT3A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100316575-A1 | MODULATING BODY WEIGHT | MAYO FOUNDATION FOR MEDICAL EDUCATION AND RESEARCH | 2010-12-16 | — | — | US | claimed |
| WO-2009099820-A2 | MODULATING BODY WEIGHT | MAYO FOUNDATION FOR MEDICAL EDUCATION AND RESEARCH (US) | 2009-08-13 | — | — | WO | claimed |
| US-20100316575-A1 | MODULATING BODY WEIGHT | MAYO FOUNDATION FOR MEDICAL EDUCATION AND RESEARCH | 2010-12-16 | — | — | US | disclosed |
| WO-2009099820-A2 | MODULATING BODY WEIGHT | MAYO FOUNDATION FOR MEDICAL EDUCATION AND RESEARCH (US) | 2009-08-13 | — | — | WO | disclosed |