Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 10/20 | 0.81 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.81 |
| ▸ | MEN1 | O00255 | 1/20 | 0.81 |
| ▸ | RECQL | P46063 | 1/20 | 0.81 |
| ▸ | HSD17B10 | Q99714 | 7/20 | 0.61 |
| ▸ | HPGD | P15428 | 5/20 | 0.61 |
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.59 |
| ▸ | ESR1 | P03372 | 1/20 | 0.59 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.59 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.59 |
| ▸ | HMGB1 | P09429 | 1/20 | 0.59 |
| ▸ | TSHR | P16473 | 1/20 | 0.59 |
| ▸ | GGT1 | P19440 | 1/20 | 0.59 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.59 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.59 |
| ▸ | BLM | P54132 | 1/20 | 0.59 |
| ▸ | NAPRT | Q6XQN6 | 1/20 | 0.59 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.59 |
| ▸ | MAPT | P10636 | 2/20 | 0.58 |
| ▸ | LMNA | P02545 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13109053 | 0.98 | KDM4E (0.79) | KDM4EKMT2AMEN1RECQLHSD17B10 | |
| SCHEMBL973615 | 0.98 | KDM4E (0.79) | KDM4EKMT2AMEN1RECQLHSD17B10 | |
| SCHEMBL28416086 | 0.95 | KDM4E (0.74) | KDM4EKMT2AMEN1RECQLHSD17B10 | |
| SCHEMBL9136787 | 0.93 | KDM4E (0.72) | KDM4EKMT2AMEN1RECQLHSD17B10 | |
| SCHEMBL28878425 | 0.93 | KDM4E (0.72) | KDM4EKMT2AMEN1RECQLHSD17B10 | |
| Diaspirin SCHEMBL40799 | 0.92 | KDM4E (0.75) | KDM4EKMT2AMEN1RECQLHSD17B10 | |
| Diaspirin SCHEMBL30735506 | 0.92 | KDM4E (0.75) | KDM4EKMT2AMEN1RECQLHSD17B10 | |
| SCHEMBL29406927 | 0.92 | KDM4E (0.91) | KDM4EKMT2AMEN1RECQLHSD17B10 | |
| SCHEMBL503905 | 0.92 | KDM4E (0.91) | KDM4EKMT2AMEN1RECQLHSD17B10 | |
| SCHEMBL28417977 | 0.91 | KDM4E (0.74) | KDM4EKMT2AMEN1RECQLHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10092578-B2 | Active agents and their oligomers and polymers | POLYMERIX CORPORATION (US) | 2018-10-09 | — | — | US | disclosed |
| US-20160058776-A1 | ACTIVE AGENTS AND THEIR OLIGOMERS AND POLYMERS | RUTGERS, THE STATE UNIVERSITY OF NEW JERSEY | 2016-03-03 | — | — | US | disclosed |
| US-9108070-B2 | Active agents and their oligomers and polymers | POLYMERIX CORPORATION (US) | 2015-08-18 | — | — | US | disclosed |
| US-20130071458-A1 | ACTIVE AGENTS AND THEIR OLIGOMERS AND POLYMERS | POLYMERIX CORPORATION | 2013-03-21 | — | — | US | disclosed |
| US-20100310498-A1 | ACTIVE AGENTS AND THEIR OLIGOMERS AND POLYMERS | POLYMERIX CORPORATION | 2010-12-09 | — | — | US | disclosed |
| EP-2102144-A2 | ACTIVE AGENTS AND THEIR OLIGOMERS AND POLYMERS | Rutgers, The State University Of New Jersey (US) | 2009-09-23 | — | — | EP | disclosed |
| WO-2008034019-A2 | ACTIVE AGENTS AND THEIR OLIGOMERS AND POLYMERS | POLYMERIX CORPORATION (US) | 2008-03-20 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160058776-A1 | ACTIVE AGENTS AND THEIR OLIGOMERS AND POLYMERS | ALG1, DDOST, IDUA | KDM4E 4834/4885KMT2A 4706/4885MEN1 4465/4885 |
| US-20100310498-A1 | ACTIVE AGENTS AND THEIR OLIGOMERS AND POLYMERS | ALG1, DDOST, IDUA | KDM4E 4834/4885KMT2A 4706/4885MEN1 4465/4885 |
| US-20130071458-A1 | ACTIVE AGENTS AND THEIR OLIGOMERS AND POLYMERS | ALG1, DDOST, IDUA | KDM4E 4834/4885KMT2A 4706/4885MEN1 4465/4885 |
| US-10092578-B2 | Active agents and their oligomers and polymers | ALG1, DDOST, IDUA | KDM4E 4834/4885KMT2A 4706/4885MEN1 4465/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.