Diaspirin

Diaspirin

SCHEMBL40799

O=C(CCC(=O)Oc1ccccc1C(=O)O)Oc1ccccc1C(=O)O

nearest known ligand 0.75

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 10/20 0.75
KMT2A Q03164 2/20 0.75
MEN1 O00255 1/20 0.75
RECQL P46063 1/20 0.75
HSD17B10 Q99714 7/20 0.65
HPGD P15428 5/20 0.65
ALDH1A1 P00352 8/20 0.63
ESR1 P03372 1/20 0.63
ITGB3 P05106 1/20 0.63
ITGA2B P08514 1/20 0.63
HMGB1 P09429 1/20 0.63
TSHR P16473 1/20 0.63
GGT1 P19440 1/20 0.63
PTGS1 P23219 1/20 0.63
PTGS2 P35354 1/20 0.63
BLM P54132 1/20 0.63
NAPRT Q6XQN6 1/20 0.63
TDP1 Q9NUW8 1/20 0.63
MAPT P10636 2/20 0.61
LMNA P02545 1/20 0.56

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Diaspirin SCHEMBL30735506 1.00 KDM4E (0.75) KDM4EKMT2AMEN1RECQLHSD17B10
SCHEMBL12446248 0.94 KDM4E (0.69) KDM4EKMT2AMEN1RECQLHSD17B10
SCHEMBL3765406 0.92 KDM4E (0.81) KDM4EKMT2AMEN1RECQLHSD17B10
SCHEMBL27531407 0.91 KDM4E (0.66) KDM4EKMT2AMEN1RECQLHSD17B10
SCHEMBL14494719 0.91 KDM4E (0.69) KDM4EKMT2AMEN1RECQLHSD17B10
SCHEMBL13109053 0.91 KDM4E (0.79) KDM4EKMT2AMEN1RECQLHSD17B10
SCHEMBL973615 0.91 KDM4E (0.79) KDM4EKMT2AMEN1RECQLHSD17B10
SCHEMBL1697677 0.89 KDM4E (0.82) KDM4EKMT2AMEN1RECQLHSD17B10
SCHEMBL22279480 0.89 KDM4E (0.67) KDM4EKMT2AMEN1RECQLHSD17B10
SCHEMBL25946877 0.89 KDM4E (0.67) KDM4EKMT2AMEN1RECQLHSD17B10

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 681 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3492585-B1 METHOD FOR PRODUCING MESENCHYMAL STEM CELLS THAT INHIBIT PROLIFERATION OF CANCER CELLS RA JEONG CHAN (KR) 2026-02-18 EP claimed
CN-114036796-A Shear band expansion method considering uneven reduction of seabed slope soil strength 中国海洋大学 2022-02-11 CN claimed
EP-1358212-B1 METHODS FOR THE SYNTHESIS OF A MODIFIED HEMOGLOBIN SOLUTION BREONICS INC (US) 2014-04-30 EP claimed
EP-2600155-A1 sFlt-1 based diagnosis and monitoring of stroke patients Roche Diagniostics GmbH (DE) 2013-06-05 EP claimed
EP-1163010-B1 HEMOGLOBIN-ANTIOXIDANT CONJUGATES THERAPURE BIOPHARMA INC (CA) 2012-12-12 EP claimed
WO-2011075799-A2 ORAL ANTIDEPRESSANT FORMULATION MENDLEWICZ JULIEN (BE) 2011-06-30 WO claimed
US-20100311641-A1 PEPTIDE-BASED BODY SURFACE COLORING REAGENTS E. I. DU PONT DE NEMOURS AND COMPANY (US) 2010-12-09 US claimed
US-20100189797-A1 ORAL ANTIDEPRESSANT FORMULATION MENDLEWICZ JULIEN 2010-07-29 US claimed
US-7662805-B2 Mixture of antidepressant such as serotonine receptor antagonist, with acetylsalicylic acid MENDLEWICZ JULIEN 2010-02-16 US claimed
EP-1677772-B1 ORAL ANTIDEPRESSANT FORMULATION COMPRISING ACETYLSALICYLIC ACID TO ACCELERATE ONSET OF ACTION KRIWIN PHILIPPE (BE) 2009-08-26 EP claimed
WO-1996015805-A1 HEMOGLOBIN THERAPY IN HEMODIALYSIS BAXTER INTERNATIONAL INC. (US) 1996-05-30 WO claimed
EP-0700298-A1 THERAPEUTIC USE OF HEMOGLOBIN IN THE TREATMENT OF BLOOD VESSEL BLOCKAGE BAXTER INTERNATIONAL INC. (a Delaware corporation) (US) 1996-03-13 EP claimed
WO-1995026195-A1 THERAPEUTIC USE OF HEMOGLOBIN IN THE TREATMENT OF BLOOD VESSEL BLOCKAGE BAXTER INTERNATIONAL INC. (US) 1995-10-05 WO claimed
US-5248766-A Oxirane-modified hemoglobin based composition BAXTER INTERNATIONAL INC. (US) 1993-09-28 US claimed
EP-0496866-A1 HEMOGLOBIN-OLIGOMER BASED COMPOSITION AND METHOD TO MAKE SAME. BAXTER INT (US) 1992-08-05 EP claimed
WO-1992003153-A1 HEMOGLOBIN-OLIGOMER BASED COMPOSITION AND METHOD TO MAKE SAME BAXTER INTERNATIONAL INC. (US) 1992-03-05 WO claimed
EP-0143832-B1 MODIFIED CROSSLINKED STROMA-FREE TETRAMERIC HEMOGLOBIN TYE, Ross W. (US) 1989-02-15 EP claimed
US-4529719-A Modified crosslinked stroma-free tetrameric hemoglobin TYE ROSS W (US) 1985-07-16 US claimed
US-4474750-A Anticalculus oral composition COLGATE-PALMOLIVE COMPANY (US) 1984-10-02 US claimed
US-4080441-A BIS(O-CARBOXYPHENYL)ESTER OF AN ALIPHATIC DICARBOXYLIC ACID USED AS AN ANTISTAIN AGENT COLGATE-PALMOLIVE COMPANY (US) 1978-03-21 US claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20100311641-A1 PEPTIDE-BASED BODY SURFACE COLORING REAGENTS CUTA, PRAP1, RBP1 KDM4E 4802/4885KMT2A 3436/4885MEN1 1271/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.