Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 10/20 | 0.79 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.79 |
| ▸ | MEN1 | O00255 | 1/20 | 0.79 |
| ▸ | RECQL | P46063 | 1/20 | 0.79 |
| ▸ | HSD17B10 | Q99714 | 7/20 | 0.59 |
| ▸ | HPGD | P15428 | 5/20 | 0.59 |
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.58 |
| ▸ | ESR1 | P03372 | 1/20 | 0.58 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.58 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.58 |
| ▸ | HMGB1 | P09429 | 1/20 | 0.58 |
| ▸ | TSHR | P16473 | 1/20 | 0.58 |
| ▸ | GGT1 | P19440 | 1/20 | 0.58 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.58 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.58 |
| ▸ | BLM | P54132 | 1/20 | 0.58 |
| ▸ | NAPRT | Q6XQN6 | 1/20 | 0.58 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.58 |
| ▸ | MAPT | P10636 | 1/20 | 0.56 |
| ▸ | LMNA | P02545 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13109053 | 1.00 | KDM4E (0.79) | KDM4EKMT2AMEN1RECQLHSD17B10 | |
| SCHEMBL3765406 | 0.98 | KDM4E (0.81) | KDM4EKMT2AMEN1RECQLHSD17B10 | |
| SCHEMBL9136787 | 0.95 | KDM4E (0.72) | KDM4EKMT2AMEN1RECQLHSD17B10 | |
| SCHEMBL28878425 | 0.95 | KDM4E (0.72) | KDM4EKMT2AMEN1RECQLHSD17B10 | |
| SCHEMBL28416086 | 0.93 | KDM4E (0.74) | KDM4EKMT2AMEN1RECQLHSD17B10 | |
| SCHEMBL727072 | 0.92 | KDM4E (0.88) | KDM4EKMT2AMEN1RECQLHSD17B10 | |
| SCHEMBL13983812 | 0.92 | KDM4E (0.73) | KDM4EKMT2AMEN1RECQLHSD17B10 | |
| SCHEMBL1858148 | 0.92 | KDM4E (0.88) | KDM4EKMT2AMEN1RECQLHSD17B10 | |
| SCHEMBL725982 | 0.92 | KDM4E (0.88) | KDM4EKMT2AMEN1RECQLHSD17B10 | |
| SCHEMBL16800398 | 0.92 | KDM4E (0.88) | KDM4EKMT2AMEN1RECQLHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7875283-B2 | A stent coated with hydrophobic polymer having water-labile bonds and strength to withstand forces of the vascular systems and also biodegrades on its surface rather than bulk erosion; mechanical properties; drug delivery; a polyester,-anhydride or -amide having the monomer, trimellitylimidotyrosine | ADVANCED CARDIOVASCULAR SYSTEMS, INC. (US) | 2011-01-25 | — | — | US | claimed |
| US-20050232971-A1 | Biodegradable polymers for use with implantable medical devices | HOSSAINY SYED F | 2005-10-20 | — | — | US | claimed |
| US-7875283-B2 | A stent coated with hydrophobic polymer having water-labile bonds and strength to withstand forces of the vascular systems and also biodegrades on its surface rather than bulk erosion; mechanical properties; drug delivery; a polyester,-anhydride or -amide having the monomer, trimellitylimidotyrosine | ADVANCED CARDIOVASCULAR SYSTEMS, INC. (US) | 2011-01-25 | — | — | US | disclosed |
| US-20100291181-A1 | THERAPEUTIC DEVICES FOR PATTERNED CELL GROWTH | RUTGERS, THE STATE UNIVERSITY OF NEW JERSEY (US) | 2010-11-18 | — | — | US | disclosed |
| US-20100291181-A1 | THERAPEUTIC DEVICES FOR PATTERNED CELL GROWTH | RUTGERS, THE STATE UNIVERSITY OF NEW JERSEY (US) | 2010-11-18 | — | — | US | disclosed |
| US-20050232971-A1 | Biodegradable polymers for use with implantable medical devices | HOSSAINY SYED F | 2005-10-20 | — | — | US | disclosed |
| US-5434166-A | Multiple sclerosis | ELI LILLY AND COMPANY (US) | 1995-07-18 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100291181-A1 | THERAPEUTIC DEVICES FOR PATTERNED CELL GROWTH | MMP1, FGF2, FGF1 | KDM4E 2479/4885KMT2A 4326/4885MEN1 4751/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.