Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | THRB | P10828 | 6/20 | 0.48 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 6/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.43 |
| ▸ | TP53 | P04637 | 2/20 | 0.43 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.43 |
| ▸ | AKR1B10 | O60218 | 4/20 | 0.42 |
| ▸ | AKR1B1 | P15121 | 4/20 | 0.42 |
| ▸ | CA1 | P00915 | 2/20 | 0.41 |
| ▸ | CA12 | O43570 | 1/20 | 0.41 |
| ▸ | MET | P08581 | 1/20 | 0.41 |
| ▸ | CA4 | P22748 | 1/20 | 0.41 |
| ▸ | CA6 | P23280 | 1/20 | 0.41 |
| ▸ | CA5A | P35218 | 1/20 | 0.41 |
| ▸ | CA7 | P43166 | 1/20 | 0.41 |
| ▸ | CA9 | Q16790 | 1/20 | 0.41 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.41 |
| ▸ | CA5B | Q9Y2D0 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28332395 | 0.85 | THRB (0.43) | THRBHCAR2TSHRHPGDALDH1A1 | |
| SCHEMBL146134 | 0.85 | THRB (0.46) | THRBHCAR2TSHRHPGDALDH1A1 | |
| SCHEMBL193848 | 0.84 | THRB (0.66) | THRBTSHRHPGDALDH1A1TP53 | |
| SCHEMBL9806249 | 0.84 | TSHR (0.59) | THRBHCAR2TSHRHPGDALDH1A1 | |
| SCHEMBL147731 | 0.83 | THRB (0.68) | THRBHCAR2TSHRHPGDALDH1A1 | |
| SCHEMBL8031168 | 0.80 | THRB (0.56) | THRBTSHRHPGDALDH1A1CYP3A4 | |
| SCHEMBL3886442 | 0.80 | THRB (0.59) | THRBTSHRHPGDALDH1A1TP53 | |
| SCHEMBL144962 | 0.80 | TSHR (0.50) | THRBHCAR2TSHRHPGDALDH1A1 | |
| SCHEMBL40718 | 0.79 | THRB (0.67) | THRBHCAR2TSHRHPGDALDH1A1 | |
| SCHEMBL12032270 | 0.79 | TSHR (0.53) | THRBHCAR2TSHRHPGDALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100305327-A1 | NITROXYL COMPOUND, AND POLYMERIZATION INHIBITOR AND POLYMERIZATION INHIBITOR COMPOSITION USING SAME | ADEKA CORPORATION (JP) | 2010-12-02 | — | — | US | disclosed |
| EP-1978017-A1 | NITROXYL COMPOUND, AND POLYMERIZATION INHIBITOR AND POLYMERIZATION INHIBITOR COMPOSITION USING SAME | Adeka Corporation (JP) | 2008-10-08 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100305327-A1 | NITROXYL COMPOUND, AND POLYMERIZATION INHIBITOR AND POLYMERIZATION INHIBITOR COMPOSITION USING SAME | NOX5, NOX1, NOC2L | THRB 4747/4885HCAR2 4072/4885TSHR 4881/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.