⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3167431 | 0.85 | ALDH1A1 (0.43) | — | |
| SCHEMBL13930065 | 0.83 | ALDH1A1 (0.37) | — | |
| SCHEMBL7300417 | 0.80 | — | — | |
| SCHEMBL3168192 | 0.80 | ALDH1A1 (0.40) | — | |
| SCHEMBL3171707 | 0.78 | ALDH1A1 (0.39) | — | |
| SCHEMBL3168577 | 0.78 | ALDH1A1 (0.39) | — | |
| SCHEMBL31375385 | 0.74 | ALDH1A1 (0.43) | — | |
| SCHEMBL261604 | 0.73 | — | — | |
| SCHEMBL27658094 | 0.71 | — | — | |
| SCHEMBL678538 | 0.70 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115704810-B | Method for measuring content of 2-propyne-1-yl 1H-imidazole-1-carboxylate by high performance liquid chromatography | 张家港市国泰华荣化工新材料有限公司 | 2024-01-02 | — | — | CN | claimed |
| CN-114094186-A | Non-aqueous electrolyte and battery comprising same | 珠海冠宇电池股份有限公司 | 2022-02-25 | — | — | CN | claimed |
| CN-115704810-A | Method for determining content of 2-propyn-1-yl 1H-imidazole-1-carboxylate by high performance liquid chromatography | 张家港市国泰华荣化工新材料有限公司 | 2023-02-17 | — | — | CN | disclosed |
| WO-2022193179-A1 | ELECTROLYTE AND ELECTROCHEMICAL DEVICE COMPRISING SAME | 宁德新能源科技有限公司 | 2022-09-22 | — | — | WO | disclosed |
| CN-114094186-A | Non-aqueous electrolyte and battery comprising same | 珠海冠宇电池股份有限公司 | 2022-02-25 | — | — | CN | disclosed |
| EP-2029570-B1 | FUSED THIOPHENE DERIVATIVES AS KINASE INHIBITORS | UCB PHARMA SA (BE) | 2014-10-15 | — | — | EP | disclosed |
| US-8324204-B2 | Fused thiophene derivatives as kinase inhibitors | UCB PHARMA SA (BE) | 2012-12-04 | — | — | US | disclosed |
| US-20100305066-A1 | Fused Thiophene Derivatives as Kinase Inhibitors | UCB PHARMA S.A. (BE) | 2010-12-02 | — | — | US | disclosed |
| WO-2009122148-A1 | FUSED THIOPHENE AND THIAZOLE DERIVATIVES AS PI3K KINASE INHIBITORS | UCB PHARMA S.A. (BE) | 2009-10-08 | — | — | WO | disclosed |
| WO-2009071895-A1 | FUSED THIAZOLE AND THIOPHENE DERIVATIVES AS KINASE INHIBITORS | UCB PHARMA S.A. (BE) | 2009-06-11 | — | — | WO | disclosed |
| WO-2009071890-A1 | TRICYCLIC KINASE INHIBITORS | UCB PHARMA S.A. (BE) | 2009-06-11 | — | — | WO | disclosed |
| EP-2029570-A1 | FUSED THIOPHENE DERIVATIVES AS KINASE INHIBITORS | UCB Pharma S.A. (BE) | 2009-03-04 | — | — | EP | disclosed |
| WO-2007141504-A1 | FUSED THIOPHENE DERIVATIVES AS KINASE INHIBITORS | UCB PHARMA S.A. (BE) | 2007-12-13 | — | — | WO | disclosed |
| EP-0214600-B1 | CEPHALOSPORIN DERIVATIVES | Otsuka Kagaku Kabushiki Kaisha (JP) | 1992-12-02 | — | — | EP | disclosed |
| US-4906623-A | 3-Imidazolium cephalosporin derivatives | OTSUKA KAGAKU KABUSHIKI KAISHA (JP) | 1990-03-06 | — | — | US | disclosed |
| EP-0214600-A2 | Cephalosporin derivatives | Otsuka Kagaku Kabushiki Kaisha (JP) | 1987-03-18 | — | — | EP | disclosed |