SCHEMBL3765826

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL3771993	0.91	LMNA (0.54)	LMNAGAAGFERALDH1A1MAPT
	SCHEMBL3772008	0.91	CCR1 (0.59)	CYP2C19CCR1
	SCHEMBL3767834	0.91	LMNA (0.50)	LMNAGAAALDH1A1MAPTKDM4E
	SCHEMBL3765873	0.88	GFER (0.55)	LMNAGAAGFERALDH1A1MAPT
	SCHEMBL3773446	0.87	GAA (0.69)	LMNAGAAGFERALDH1A1MAPT
	SCHEMBL3767437	0.86	GFER (0.59)	LMNAGAAGFERALDH1A1MAPT
	SCHEMBL3777260	0.84	NPSR1 (0.49)	LMNAGAAGFERALDH1A1MAPT
	SCHEMBL3765245	0.83	RAB9A (0.55)	LMNAGAAGFERALDH1A1MAPT
	SCHEMBL3768910	0.83	MAPT (0.56)	LMNAGAAGFERALDH1A1MAPT
	SCHEMBL14608867	0.83	GAA (0.53)	LMNAGAAALDH1A1MAPTPOLB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.