SCHEMBL3766975

SCHEMBL3766975

c1ccc(C2Oc3ccccc3O2)cc1

nearest known ligand 0.45

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 3/20 0.45
KMT2A Q03164 3/20 0.45
LMNA P02545 2/20 0.45
POLB P06746 1/20 0.45
CYP2C19 P33261 1/20 0.44
CYP19A1 P11511 2/20 0.41
NISCH Q9Y2I1 1/20 0.41
KDM4E B2RXH2 1/20 0.41
ADORA3 P0DMS8 1/20 0.41
AR P10275 1/20 0.41
MAOB P27338 1/20 0.41
HSD17B10 Q99714 1/20 0.41
SIRT1 Q96EB6 9/20 0.40
TSHR P16473 1/20 0.40
SIRT2 Q8IXJ6 2/20 0.36
SIRT5 Q9NXA8 2/20 0.36
CA2 P00918 1/20 0.35
ALDH1A1 P00352 1/20 0.35
MAPT P10636 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3140434 0.80 NISCH (0.36) MEN1KMT2ALMNAPOLBCYP2C19
SCHEMBL30362056 0.80 CYP19A1 (0.53) MEN1KMT2ALMNAPOLBCYP19A1
SCHEMBL11883260 0.80 CYP19A1 (0.53) MEN1KMT2ALMNAPOLBCYP19A1
SCHEMBL28442693 0.79 NISCH (0.35) MEN1KMT2ALMNAPOLBNISCH
SCHEMBL25015609 0.79 CYP19A1 (0.43) MEN1KMT2ALMNAPOLBCYP2C19
SCHEMBL11547380 0.79 SIRT1 (0.39) MEN1KMT2ALMNAPOLBCYP2C19
SCHEMBL4013126 0.79 MEN1 (0.36) MEN1KMT2ALMNAPOLBCYP2C19
SCHEMBL2269003 0.79 CYP19A1 (0.47) MEN1KMT2ACYP19A1ARMAOB
SCHEMBL21347859 0.79 MEN1 (0.47) MEN1KMT2ALMNAPOLBCYP2C19
SCHEMBL30362163 0.79 CYP19A1 (0.43) MEN1KMT2ALMNAPOLBCYP2C19

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4720136-A2 LIGHT ADJUSTABLE INTRAOCULAR LENSES WITH A CAGED PHOTOINITIATOR RxSight, Inc. (US) 2026-04-08 EP claimed
WO-2024249726-A2 LIGHT ADJUSTABLE INTRAOCULAR LENSES WITH A CAGED PHOTOINITIATOR RXSIGHT, INC. (US) 2024-12-05 WO claimed
US-20240398551-A1 LIGHT ADJUSTABLE INTRAOCULAR LENSES WITH A CAGED PHOTOINITIATOR RXSIGHT, INC. 2024-12-05 US claimed
EP-4720136-A2 LIGHT ADJUSTABLE INTRAOCULAR LENSES WITH A CAGED PHOTOINITIATOR RxSight, Inc. (US) 2026-04-08 EP disclosed
WO-2024249726-A2 LIGHT ADJUSTABLE INTRAOCULAR LENSES WITH A CAGED PHOTOINITIATOR RXSIGHT, INC. (US) 2024-12-05 WO disclosed
US-20240398551-A1 LIGHT ADJUSTABLE INTRAOCULAR LENSES WITH A CAGED PHOTOINITIATOR RXSIGHT, INC. 2024-12-05 US disclosed
US-7847110-B2 Method for producing optionally substituted methylenedioxybenzene RHODIA CHIMIE (FR) 2010-12-07 US disclosed
EP-1737837-B1 METHOD FOR PRODUCING OPTIONALLY SUBSTITUTED METHYLENEDIOXYBENZENE RHODIA CHIMIE SA (FR) 2008-02-27 EP disclosed
US-20080021228-A1 Method For Producing Optionally Substituted Methylenedioxybenzene RHODIA CHIMIE (FR) 2008-01-24 US disclosed
EP-1737837-A1 METHOD FOR PRODUCING OPTIONALLY SUBSTITUTED METHYLENEDIOXYBENZENE RHODIA CHIMIE (FR) 2007-01-03 EP disclosed
WO-2005108385-A1 METHOD FOR PRODUCING OPTIONALLY SUBSTITUTED METHYLENEDIOXYBENZENE RHODIA CHIMIE (FR) 2005-11-17 WO disclosed
US-4155915-A POSTEMERGENCE AND PREEMERGENCE HERBICIDES SCHERING AKTIENGESELLSCHAFT (DE) 1979-05-22 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20080021228-A1 Method For Producing Optionally Substituted Methylenedioxybenzene COMT, INMT, DDT MEN1 1461/4885KMT2A 125/4885LMNA 4497/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.