SCHEMBL3767022

SCHEMBL3767022

CC(C)CNC(=O)C(NC(=O)OC(C)(C)C)c1ccc(-c2ccccc2)cc1

nearest known ligand 0.63

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
CTSS P25774 9/20 0.63
CTSK P43235 9/20 0.63
GPR88 Q9GZN0 1/20 0.47
CTSB P07858 2/20 0.47
CTSL P07711 1/20 0.46
SCN9A Q15858 1/20 0.44
BCL2 P10415 1/20 0.44
S1PR3 Q99500 1/20 0.43
ATM Q13315 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9692854 0.87 CTSS (0.58) CTSSCTSKGPR88CTSBCTSL
SCHEMBL5558475 0.86 CTSS (0.63) CTSSCTSKCTSBCTSLATM
SCHEMBL27158950 0.82 CTSK (0.56) CTSSCTSKCTSBCTSLSCN9A
SCHEMBL3759870 0.82 CTSK (0.56) CTSSCTSKCTSBCTSLSCN9A
SCHEMBL13808582 0.80 CTSS (0.54) CTSSCTSKCTSBCTSLSCN9A
SCHEMBL5552352 0.79 CTSS (0.55) CTSSCTSKCTSBCTSL
SCHEMBL11388207 0.79 CTSS (0.74) CTSSCTSKGPR88CTSBCTSL
SCHEMBL13715338 0.78 CTSK (0.57) CTSSCTSK
SCHEMBL4476718 0.78 CTSS (0.73) CTSSCTSKGPR88CTSBCTSL
SCHEMBL4200549 0.78 CTSS (0.73) CTSSCTSKGPR88CTSBCTSL

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20240065302-A1 SWEETENER COMPOSITIONS COMPRISING MOGROSIDES AND USES THEREOF FIRMENICH INCORPORATED 2024-02-29 US disclosed
US-7842324-B2 Bis-aromatic amides and their uses as sweet flavor modifiers, tastants, and taste enhancers SENOMYX, INC. (US) 2010-11-30 US disclosed
US-7842324-B2 Bis-aromatic amides and their uses as sweet flavor modifiers, tastants, and taste enhancers SENOMYX, INC. (US) 2010-11-30 US disclosed
US-7842324-B2 Bis-aromatic amides and their uses as sweet flavor modifiers, tastants, and taste enhancers SENOMYX, INC. (US) 2010-11-30 US disclosed
US-20070003680-A1 Bis-aromatic amides and their uses as sweet flavor modifiers, tastants, and taste enhancers SENOMYX, INC. 2007-01-04 US disclosed
US-20070003680-A1 Bis-aromatic amides and their uses as sweet flavor modifiers, tastants, and taste enhancers SENOMYX, INC. 2007-01-04 US disclosed
US-20070003680-A1 Bis-aromatic amides and their uses as sweet flavor modifiers, tastants, and taste enhancers SENOMYX, INC. 2007-01-04 US disclosed