SCHEMBL37677

SCHEMBL37677

Cc1cc(=O)oc2cc(N)ccc12

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 10/20 1.00
KDM4E B2RXH2 8/20 1.00
HSD17B10 Q99714 8/20 1.00
HPGD P15428 7/20 1.00
CA9 Q16790 7/20 1.00
GAA P10253 6/20 1.00
CA12 O43570 5/20 1.00
CA1 P00915 5/20 1.00
CASP1 P29466 4/20 1.00
CASP7 P55210 4/20 1.00
GLA P06280 4/20 1.00
LMNA P02545 2/20 0.64
AKR1B1 P15121 2/20 0.64
MCL1 Q07820 2/20 0.64
CYP1A2 P05177 1/20 0.64
CYP2C9 P11712 1/20 0.64
UGT1A1 P22309 1/20 0.64
MAOB P27338 1/20 0.64
KDR P35968 1/20 0.64
HSD17B3 P37058 1/20 0.64

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29645144 1.00 ALDH1A1 (1.00) ALDH1A1KDM4EHSD17B10HPGDCA9
SCHEMBL28806970 1.00 ALDH1A1 (1.00) ALDH1A1KDM4EHSD17B10HPGDCA9
Hydrochloric Acid SCHEMBL30762676 0.98 ALDH1A1 (0.96) ALDH1A1KDM4EHSD17B10HPGDCA9
Hydrochloric Acid SCHEMBL2545954 0.98 ALDH1A1 (0.96) ALDH1A1KDM4EHSD17B10HPGDCA9
Bromide SCHEMBL30457821 0.98 ALDH1A1 (0.96) ALDH1A1KDM4EHSD17B10HPGDCA9
SCHEMBL1037558 0.98 ALDH1A1 (0.96) ALDH1A1KDM4EHSD17B10HPGDCA9
Hydrochloric Acid SCHEMBL567469 0.98 ALDH1A1 (0.96) ALDH1A1KDM4EHSD17B10HPGDCA9
Bromide SCHEMBL18007249 0.98 ALDH1A1 (0.96) ALDH1A1KDM4EHSD17B10HPGDCA9
Bromide SCHEMBL28878217 0.96 ALDH1A1 (0.93) ALDH1A1KDM4EHSD17B10HPGDCA9
Acetic Acid SCHEMBL3998167 0.92 ALDH1A1 (0.84) ALDH1A1KDM4EHSD17B10HPGDCA9

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Appears in 20644 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-122094930-A Recovery of purified material from crude mixture 2026-05-26 CN claimed
CN-122075734-A Conjugates comprising tetrapeptides, methods of making, intermediates and uses thereof 2026-05-26 CN claimed
US-12636373-B2 Prodrugs with a tridentate self-immolative linker THE GENERAL HOSPITAL CORPORATION (US) 2026-05-26 US claimed
US-20260137650-A1 MODULATORS OF RAR RELATED ORPHAN RECEPTORS (RORs) 11949098 CANADA INC (CA) 2026-05-21 US claimed
CN-122010154-A Method for preparing high-whiteness cubic nano calcium carbonate at low temperature 湖北三峡实验室 2026-05-12 CN claimed
EP-4731992-A1 GREEN ENERGY SOURCES AUTHENTICATION AND COMPLIANCE TESTING Authentix, Inc. (US) 2026-04-29 EP claimed
US-12611439-B2 Ionic self-assembling peptides 3-D MATRIX, LTD. (JP) 2026-04-28 US claimed
EP-4709383-A1 INVERSE AGONISTS OF RAR RELATED ORPHAN RECEPTORS (RORS) 11949098 Canada Inc. (CA) 2026-03-18 EP claimed
US-12577324-B2 Antibodies having specificity to HER4 and uses thereof INSERM (INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE) (FR) 2026-03-17 US claimed
US-20260053146-A1 MASTOPARAN PEPTIDES AS TREATMENT AGAINST LIBERIBACTER-CAUSED CROP DISEASES US AGRICULTURE (US) 2026-02-26 US claimed
WO-1986000341-A1 PROCESSES AND MATERIALS FOR CARRYING OUT MICROCHEMICAL AND MICROBIOLOGICAL TESTS UNILEVER NV (NL) 1986-01-16 WO claimed
US-4536322-A Fluorescent corrosive fluoride solution UNION CARBIDE CORPORATION (US) 1985-08-20 US claimed
EP-0140347-A2 Fluorescent corrosive fluoride solution UNION CARBIDE CORPORATION (US) 1985-05-08 EP claimed
EP-0122148-A1 Method of measuring the number of cells of microorganisms AJINOMOTO CO., INC. (JP) 1984-10-17 EP claimed
EP-0088695-A2 Antibody conjugates CYTOGEN CORPORATION (US) 1983-09-14 EP claimed
US-4335204-A Easily split substrates for the quantification of proteases KABI AB (SE) 1982-06-15 US claimed
US-4279810-A Easily split substrates for the quantification of proteases KABI AB (SE) 1981-07-21 US claimed
US-4257765-A Color corrected flash lamp GENERAL ELECTRIC COMPANY (US) 1981-03-24 US claimed
US-4229528-A Fluorescence method for enzyme analysis which couples aromatic amines with aromatic aldehydes SMITH ROBERT E 1980-10-21 US claimed
US-4191809-A Method of measuring enzymatic activity using novel peptide derivatives AJINOMOTO CO., INC. (JP) 1980-03-04 US claimed