SCHEMBL29645144

SCHEMBL29645144

Cc1cc(=O)oc2cc(N)ccc12

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ ALDH1A1 P00352 10/20 1.00
▸ KDM4E B2RXH2 8/20 1.00
▸ HSD17B10 Q99714 8/20 1.00
▸ HPGD P15428 7/20 1.00
▸ CA9 Q16790 7/20 1.00
▸ GAA P10253 6/20 1.00
▸ CA12 O43570 5/20 1.00
▸ CA1 P00915 5/20 1.00
▸ CASP1 P29466 4/20 1.00
▸ CASP7 P55210 4/20 1.00
▸ GLA P06280 4/20 1.00
▸ LMNA P02545 2/20 0.64
▸ AKR1B1 P15121 2/20 0.64
▸ MCL1 Q07820 2/20 0.64
▸ CYP1A2 P05177 1/20 0.64
▸ CYP2C9 P11712 1/20 0.64
▸ UGT1A1 P22309 1/20 0.64
▸ MAOB P27338 1/20 0.64
▸ KDR P35968 1/20 0.64
▸ HSD17B3 P37058 1/20 0.64

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL37677 1.00 ALDH1A1 (1.00) ALDH1A1KDM4EHSD17B10HPGDCA9
SCHEMBL28806970 1.00 ALDH1A1 (1.00) ALDH1A1KDM4EHSD17B10HPGDCA9
Hydrochloric Acid SCHEMBL30762676 0.98 ALDH1A1 (0.96) ALDH1A1KDM4EHSD17B10HPGDCA9
Hydrochloric Acid SCHEMBL567469 0.98 ALDH1A1 (0.96) ALDH1A1KDM4EHSD17B10HPGDCA9
SCHEMBL1037558 0.98 ALDH1A1 (0.96) ALDH1A1KDM4EHSD17B10HPGDCA9
Hydrochloric Acid SCHEMBL2545954 0.98 ALDH1A1 (0.96) ALDH1A1KDM4EHSD17B10HPGDCA9
Bromide SCHEMBL18007249 0.98 ALDH1A1 (0.96) ALDH1A1KDM4EHSD17B10HPGDCA9
Bromide SCHEMBL30457821 0.98 ALDH1A1 (0.96) ALDH1A1KDM4EHSD17B10HPGDCA9
Bromide SCHEMBL28878217 0.96 ALDH1A1 (0.93) ALDH1A1KDM4EHSD17B10HPGDCA9
Acetic Acid SCHEMBL3998167 0.92 ALDH1A1 (0.84) ALDH1A1KDM4EHSD17B10HPGDCA9

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 18 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4624903-A1 LIQUID SPRAY ANALYSIS Rolls-Royce plc (GB) 2025-10-01 — — EP claimed
US-20250297956-A1 LIQUID SPRAY ANALYSIS ROLLS-ROYCE PLC (GB) 2025-09-25 — — US claimed
EP-4624903-A1 LIQUID SPRAY ANALYSIS Rolls-Royce plc (GB) 2025-10-01 — — EP disclosed
US-20250297956-A1 LIQUID SPRAY ANALYSIS ROLLS-ROYCE PLC (GB) 2025-09-25 — — US disclosed
CN-116947797-B Fluorescent probe for two-photon detection of carboxylesterase, preparation method and application 山东师范大学 2025-05-30 — — CN disclosed
US-12310969-B2 Antithrombotic compositions and methods for using same UNIVERSITY OF NORTH TEXAS (US) 2025-05-27 — — US disclosed
CN-114696192-B Tunable laser based on solvent response type photonic crystal 中国科学院理化技术研究所 2025-03-14 — — CN disclosed
CN-119285594-A 7-Aminobenzopyrone or 7-aminoquinolinone compound and application thereof 浙江大学金华研究院 2025-01-10 — — CN disclosed
US-20240409597-A1 MODIFIED POLYNUCLEOTIDES FOR THE PRODUCTION OF SECRETED PROTEINS ARES CAPITAL CORPORATION, AS AGENT 2024-12-12 — — US disclosed
US-20240041922-A1 METHODS AND COMPOSITIONS MONASH UNIVERSITY (AU) 2024-02-08 — — US disclosed
CN-116947797-A Fluorescent probe for two-photon detection of carboxylesterase, preparation method and application 山东师范大学 2023-10-27 — — CN disclosed
CN-112252058-B Dyeing method of textile fabric and obtained fabric 苏州宝进纺织品有限公司 2023-07-07 — — CN disclosed
EP-4138879-A1 METHODS AND COMPOSITIONS Monash University (AU) 2023-03-01 — — EP disclosed
US-20230054313-A1 ANTITHROMBOTIC COMPOSITIONS AND METHODS FOR USING SAME UNIV NORTH TEXAS (US) 2023-02-23 — — US disclosed
EP-3327091-B1 EPOXY FUNCTIONAL COMPOSITION PROTECTING DYES FROM PHOTO-DEGRADATION AND CURED COATINGS PREPARED THEREFROM ESSILOR INT (FR) 2023-01-18 — — EP disclosed
CN-114869863-A Multifunctional composite stent and preparation method and application thereof 中山大学附属第三医院 2022-08-09 — — CN disclosed
CN-113270786-B Solid dye laser gain medium and preparation method thereof 南京邮电大学 2022-08-05 — — CN disclosed
CN-114696192-A Tunable laser based on solvent response type photonic crystal 中国科学院理化技术研究所 2022-07-01 — — CN disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20240409597-A1 MODIFIED POLYNUCLEOTIDES FOR THE PRODUCTION OF SECRETED PROTEINS MSH2, POLRMT, SARNP ALDH1A1 4456/4885KDM4E 4720/4885HSD17B10 4735/4885
US-12310969-B2 Antithrombotic compositions and methods for using same SERPINC1, TFPI, TFPI2 ALDH1A1 2029/4885KDM4E 2819/4885HSD17B10 2902/4885
US-20230054313-A1 ANTITHROMBOTIC COMPOSITIONS AND METHODS FOR USING SAME SERPINC1, TFPI, TFPI2 ALDH1A1 2029/4885KDM4E 2819/4885HSD17B10 2902/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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