Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA1 | P00915 | 10/20 | 0.59 |
| ▸ | CA2 | P00918 | 10/20 | 0.59 |
| ▸ | CA9 | Q16790 | 1/20 | 0.40 |
| ▸ | FAAH | O00519 | 3/20 | 0.39 |
| ▸ | CES1 | P23141 | 3/20 | 0.39 |
| ▸ | MMP1 | P03956 | 2/20 | 0.38 |
| ▸ | MMP2 | P08253 | 2/20 | 0.38 |
| ▸ | MMP9 | P14780 | 2/20 | 0.38 |
| ▸ | MMP8 | P22894 | 2/20 | 0.38 |
| ▸ | MMP13 | P45452 | 2/20 | 0.38 |
| ▸ | MAOA | P21397 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8007555 | 0.84 | CA2 (0.54) | CA1CA2CA9FAAHCES1 | |
| SCHEMBL8441263 | 0.82 | CA2 (0.53) | CA1CA2CA9FAAHCES1 | |
| SCHEMBL8077441 | 0.82 | CA2 (0.53) | CA1CA2CA9FAAHCES1 | |
| SCHEMBL575499 | 0.82 | CA2 (0.53) | CA1CA2CA9MMP1MMP2 | |
| SCHEMBL575650 | 0.82 | CA2 (0.53) | CA1CA2CA9MMP1MMP2 | |
| SCHEMBL575456 | 0.82 | CA2 (0.53) | CA1CA2CA9MMP1MMP2 | |
| SCHEMBL576013 | 0.80 | CA2 (0.51) | CA1CA2CA9MMP1MMP2 | |
| SCHEMBL2261974 | 0.79 | CA2 (0.68) | CA1CA2CA9FAAHMMP1 | |
| SCHEMBL3767941 | 0.79 | CA2 (0.38) | CA1CA2CA9FAAHCES1 | |
| SCHEMBL4625553 | 0.79 | CA2 (0.55) | CA1CA2CA9FAAHCES1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010007363-A2 | PREPARATION OF FLUORINE-LABELLED COMPOUNDS | ISIS INNOVATION LIMITED (GB) | 2010-01-21 | — | — | WO | disclosed |