SCHEMBL8007555

SCHEMBL8007555

O=S(=O)(OCCCCc1ccccc1)C(F)(F)F

nearest known ligand 0.63

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
CA2 P00918 3/20 0.54
CA1 P00915 2/20 0.54
CA9 Q16790 1/20 0.47
FAAH O00519 3/20 0.46
CES1 P23141 3/20 0.46
IDO1 P14902 1/20 0.43
FFAR1 O14842 1/20 0.43
MEN1 O00255 1/20 0.42
KMT2A Q03164 1/20 0.42
MGLL Q99685 2/20 0.42
MAOA P21397 1/20 0.41
LMNA P02545 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8077441 0.98 CA2 (0.53) CA2CA1CA9FAAHCES1
SCHEMBL8441263 0.98 CA2 (0.53) CA2CA1CA9FAAHCES1
SCHEMBL4625553 0.95 CA2 (0.55) CA2CA1CA9FAAHCES1
SCHEMBL8551008 0.89 CA2 (0.48) CA2CA1CA9FAAHCES1
SCHEMBL6586107 0.87 CA2 (0.68) CA2CA1CA9FAAHCES1
SCHEMBL17168317 0.85 CA2 (0.54) CA2CA1CA9FFAR1
SCHEMBL27525477 0.85 CA2 (0.54) CA2CA1FAAHCES1FFAR1
SCHEMBL27525475 0.84 CA2 (0.52) CA2CA1
SCHEMBL3767944 0.84 CA1 (0.59) CA2CA1CA9FAAHCES1
SCHEMBL8552342 0.82 FAAH (0.46) CA2CA1CA9FAAHCES1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6136790-A MULTIETHER COMPOUNDS AS ANTITICKING AGENTS GLYCOREX AB (SE) 2000-10-24 US disclosed
US-5693621-A INHIBITING BINDING OF SELECTIN TO CARBOHYDRATE LIGANDS HOECHST AKTIENGESELLSCHAFT (DE) 1997-12-02 US disclosed
EP-0671409-A2 Malonic acid derivatives having anti-adhesive properties HOECHST AKTIENGESELLSCHAFT (DE) 1995-09-13 EP disclosed