SCHEMBL3768

SCHEMBL3768

Brc1cccc(-c2ccccc2)n1

nearest known ligand 0.68

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 2/20 0.68
KMT2A Q03164 2/20 0.68
RAB9A P51151 1/20 0.68
ASIC3 Q9UHC3 1/20 0.56
ALDH1A1 P00352 2/20 0.43
HPGD P15428 2/20 0.43
POLB P06746 1/20 0.43
MAPT P10636 1/20 0.43
HSD17B10 Q99714 1/20 0.43
ADORA2A P29274 4/20 0.42
AURKA O14965 1/20 0.42
HSP90AA1 P07900 1/20 0.42
PRKACA P17612 1/20 0.42
ADORA1 P30542 4/20 0.41
L3MBTL1 Q9Y468 2/20 0.41
SMN1; SMN2 Q16637 1/20 0.41
KDR P35968 1/20 0.41
IDO1 P14902 1/20 0.40
METAP2 P50579 1/20 0.40
KEAP1 Q14145 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL23598723 0.96 MEN1 (0.70) MEN1KMT2ARAB9AASIC3ALDH1A1
SCHEMBL28670824 0.96 RAB9A (0.62) MEN1KMT2ARAB9AASIC3ALDH1A1
SCHEMBL16406991 0.90 MEN1 (0.61) MEN1KMT2ARAB9AASIC3ALDH1A1
SCHEMBL23196588 0.88 MEN1 (0.59) MEN1KMT2ARAB9AASIC3ALDH1A1
SCHEMBL20481867 0.87 MEN1 (0.52) MEN1KMT2ARAB9AASIC3ADORA2A
SCHEMBL23312633 0.83 L3MBTL1 (0.47) MEN1KMT2ARAB9AASIC3ALDH1A1
SCHEMBL19412113 0.83 MEN1 (0.46) MEN1KMT2ARAB9AASIC3ALDH1A1
SCHEMBL23598431 0.82 MEN1 (0.52) MEN1KMT2ARAB9AASIC3ALDH1A1
SCHEMBL2263820 0.82 MEN1 (0.53) MEN1KMT2ARAB9AALDH1A1HPGD
SCHEMBL16675045 0.82 RAB9A (0.44) MEN1KMT2ARAB9AASIC3ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 333 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-111978951-A Organic light-emitting material, manufacturing method thereof and OLED device 上海和辉光电有限公司 2020-11-24 CN claimed
CN-122036808-A Organic electroluminescent material and device 环球展览公司 2026-05-15 CN disclosed
US-20260136752-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION (US) 2026-05-14 US disclosed
US-12534458-B2 Spiropiperidine allosteric modulators of nicotinic acetylcholine receptors MERCK SHARP & DOHME LLC (US) 2026-01-27 US disclosed
US-12503643-B2 Material for organic electroluminescence element, and organic electroluminescence element NIPPON STEEL CHEMICAL & MATERIAL CO., LTD. (JP) 2025-12-23 US disclosed
US-20250107429-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION (US) 2025-03-27 US disclosed
US-12201011-B2 Organic electroluminescent materials and devices UNIVERSAL DISPLAY CORPORATION (US) 2025-01-14 US disclosed
US-20240130220-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION (US) 2024-04-18 US disclosed
EP-3615514-B1 PROPIONIC ACID DERIVATIVES AND METHODS OF USE THEREOF AVIARA PHARMACEUTICALS INC (US) 2023-11-22 EP disclosed
EP-3615514-B1 PROPIONIC ACID DERIVATIVES AND METHODS OF USE THEREOF AVIARA PHARMACEUTICALS INC (US) 2023-11-22 EP disclosed
US-20020058606-A1 Treatment of sexual dysfunction WARNER-LAMBERT COMPANY 2002-05-16 US disclosed
US-6066597-A Herbicidal 2-(hetero)aryloxy-6-arylpyridines and 2-aryl-4-(hetero)aryloxy-6-arylpyridines and 2-aryl-4-(hetero)aryloxypyrimidines AMERICAN CYANAMID COMPANY (US) 2000-05-23 US disclosed
US-6008161-A Herbicidal 2-(hetero)aryloxy-6-arylpyridines and 2-aryl-4-(hetero) aryloxypyrimidines AMERICAN CYANAMID COMPANY (US) 1999-12-28 US disclosed
US-5849758-A Herbicidal 2, 6-disubstituted pyridines and 2, 4-disubstituted pyrimidines AMERICAN CYANAMID COMPANY (US) 1998-12-15 US disclosed
US-5824624-A HERBICIDES WITH CARRIERS OR SURFACTANTS AMERICAN CYANAMID COMPANY (US) 1998-10-20 US disclosed
CN-1175578-A Herbicidal 2, 6 -disubstituted pyridines and 2, 4 -disubstituted pyrimidines AMERICAN CYANAMID CO (US) 1998-03-11 CN disclosed
EP-0823431-A1 Herbicidal 2,6-disubstituted pyridines and 2,4-disubstituted pyrimidines American Cyanamid Company (US) 1998-02-11 EP disclosed
CN-1143078-A 2,6-twice substituted pyridine and 2,4-twice substituted pyrimidine for berbicide AMERICAN CYANAMID CO (US) 1997-02-19 CN disclosed
US-5576338-A ANTIALLERGENS, ANTIHISTAMINES, ANTIINFLAMMATORY AGENTS AND CYTOPROTECTIVE AGENTS FOR CARDIOVASCULAR DISORDERS MERCK FROSST CANADA, INC. (CA) 1996-11-19 US disclosed
EP-0723960-A1 Herbicidal 2,6-disubstituted pyridines and 2,4-disubstituted pyrimidines American Cyanamid Company (US) 1996-07-31 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12534458-B2 Spiropiperidine allosteric modulators of nicotinic acetylcholine receptors CHRNA6, CHRNA7, CHRNA5 MEN1 4861/4885KMT2A 3415/4885RAB9A 771/4885
US-12201011-B2 Organic electroluminescent materials and devices NSD3, CCND3, DRD3 MEN1 2899/4885KMT2A 804/4885RAB9A 3374/4885
US-20020058606-A1 Treatment of sexual dysfunction BRS3, GNRHR, VIPR2 MEN1 2314/4885KMT2A 4654/4885RAB9A 1217/4885
US-20250107429-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES NSD3, CCND3, DRD3 MEN1 2899/4885KMT2A 804/4885RAB9A 3374/4885
US-20260136752-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES LBR, GLRB, GLRA1 MEN1 3787/4885KMT2A 3499/4885RAB9A 995/4885
US-20240130220-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES OCIAD2, OCIAD1, ICOSLG MEN1 2439/4885KMT2A 3757/4885RAB9A 1151/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.