SCHEMBL3768394

SCHEMBL3768394

CC(C)CCCC(C)CCC(O)=S

nearest known ligand 0.56

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LMNA P02545 1/20 0.56
BLM P54132 1/20 0.52
PTPN1 P18031 3/20 0.46
MEN1 O00255 1/20 0.41
CYP3A4 P08684 1/20 0.41
ALOX15 P16050 1/20 0.41
KMT2A Q03164 1/20 0.41
MAPT P10636 1/20 0.33
PTPN2 P17706 1/20 0.32
CDC25B P30305 1/20 0.32
ACE2 Q9BYF1 1/20 0.31
KDM4C Q9H3R0 2/20 0.31
KDM4A O75164 1/20 0.31
PHF8 Q9UPP1 1/20 0.31
KDM2A Q9Y2K7 1/20 0.31
PTGS1 P23219 1/20 0.31
PDE4A P27815 1/20 0.31
SNCA P37840 1/20 0.31
PDE3A Q14432 1/20 0.31
CA12 O43570 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7128633 0.80
SCHEMBL3625316 0.80
SCHEMBL7758037 0.78 ACE2 (0.55) LMNAMAPTACE2
SCHEMBL18920279 0.78 ACE2 (0.55) LMNAMAPTACE2
SCHEMBL22471935 0.78 LMNA (0.43) LMNABLMPTPN1KDM4CKDM4A
SCHEMBL277518 0.77 BLM (0.63) LMNABLMPTPN1MEN1CYP3A4
SCHEMBL1116070 0.77 BLM (0.63) LMNABLMPTPN1MEN1CYP3A4
SCHEMBL10537164 0.77 BLM (0.63) LMNABLMPTPN1MEN1CYP3A4
SCHEMBL27601852 0.77 BLM (0.63) LMNABLMPTPN1MEN1CYP3A4
SCHEMBL29352977 0.77 BLM (0.63) LMNABLMPTPN1MEN1CYP3A4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1892256-B1 AROMATIC POLYMER SUMITOMO CHEMICAL CO (JP) 2014-03-19 EP disclosed
US-7852434-B2 Aromatic polymer SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2010-12-14 US disclosed
US-20090207346-A1 Aromatic polymer SUMITOMO CHEMICAL COMPANY,LIMITED (JP) 2009-08-20 US disclosed
US-20090096355-A1 Aromatic Graft Polymer SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2009-04-16 US disclosed
EP-1892257-A1 AROMATIC GRAFT POLYMER Sumitomo Chemical Company, Limited (JP) 2008-02-27 EP disclosed
EP-1892256-A1 AROMATIC POLYMER Sumitomo Chemical Company, Limited (JP) 2008-02-27 EP disclosed