SCHEMBL376856

SCHEMBL376856

C#CCCC1CC1

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL236468 0.88
SCHEMBL235643 0.86 CYP1A2 (0.42)
SCHEMBL21508603 0.82
SCHEMBL23245592 0.82 DAO (0.33)
Hydrochloric Acid SCHEMBL31747446 0.80 GNAO1 (0.36)
SCHEMBL3635697 0.75
SCHEMBL23245521 0.75
SCHEMBL23280287 0.72
SCHEMBL22048102 0.71 MAOA (0.30)
SCHEMBL387459 0.71 CYP1A2 (0.50)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2023166172-A1 SMALL MOLECULE MODULATORS OF IL-17 LEO PHARMA A/S (DK) 2023-09-07 WO disclosed
EP-1310494-B1 PPAR (delta) ACTIVATORS NIPPON CHEMIPHAR CO (JP) 2012-01-25 EP disclosed
EP-0060769-B1 TERNARY COMBUSTIBLE WITH ACETYLENE CONTENT IN THE LIQUID AND GASEOUS PHASES L'AIR LIQUIDE, SOCIETE ANONYME POUR L'ETUDE ET L'EXPLOITATION DES PROCEDES GEORGES CLAUDE (FR) 1984-09-19 EP disclosed