Known targets — ChEMBL curated mechanism
ACHESCN10ASCN11ASCN1ASCN2ASCN3ASCN4ASCN5ASCN7ASCN8ASCN9A
The experimentally established mechanism targets of Gluconic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.91 |
| ▸ | PDE4A | P27815 | 1/20 | 0.67 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.52 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.50 |
| ▸ | USP2 | O75604 | 1/20 | 0.50 |
| ▸ | SLCO1B1 | Q9Y6L6 | 1/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.38 |
| ▸ | OR51E2 | Q9H255 | 1/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | CA4 | P22748 | 2/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Gluconic Acid SCHEMBL9456606 | 1.00 | LMNA (0.91) | LMNAPDE4AL3MBTL1TDP1USP2 | |
| Gluconic Acid SCHEMBL35424 | 1.00 | LMNA (0.91) | LMNAPDE4AL3MBTL1TDP1USP2 | |
| Gluconic Acid SCHEMBL161222 | 1.00 | LMNA (0.91) | LMNAPDE4AL3MBTL1TDP1USP2 | |
| SCHEMBL1876132 | 0.98 | LMNA (0.87) | LMNAPDE4AL3MBTL1TDP1USP2 | |
| Gluconic Acid SCHEMBL22442432 | 0.98 | LMNA (0.87) | LMNAPDE4AL3MBTL1TDP1USP2 | |
| Gluconic Acid SCHEMBL693435 | 0.98 | LMNA (0.95) | LMNAPDE4AL3MBTL1TDP1USP2 | |
| Gluconic Acid SCHEMBL2540660 | 0.98 | LMNA (0.87) | LMNAPDE4AL3MBTL1TDP1USP2 | |
| Gluconic Acid SCHEMBL809372 | 0.98 | LMNA (0.87) | LMNAPDE4AL3MBTL1TDP1USP2 | |
| Gluconic Acid SCHEMBL7265130 | 0.98 | LMNA (0.87) | LMNAPDE4AL3MBTL1TDP1USP2 | |
| Gluconic Acid SCHEMBL721131 | 0.98 | LMNA (0.87) | LMNAPDE4AL3MBTL1TDP1USP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021072139-A1 | FORMULATIONS FOR GASTROINTESTINAL DELIVERY OF OLIGONUCLEOTIDES | MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) | 2021-04-15 | — | — | WO | claimed |
| US-8314231-B2 | Systems, compositions, and/or methods for depolymerizing cellulose and/or starch | HYDRITE CHEMICAL CO. (US) | 2012-11-20 | — | — | US | claimed |
| WO-2008137517-A1 | SYSTEMS, COMPOSITIONS, AND/OR METHODS FOR DEPOLYMERIZING CELLULOSE AND/OR STARCH | HYDRITE CHEMICAL CO. (US) | 2008-11-13 | — | — | WO | claimed |
| US-20210235729-A1 | Method For Treating The Surface Of Plant Parts | CLARIANT INTERNATIONAL LTD. (CH) | 2021-08-05 | — | — | US | disclosed |
| WO-2021072139-A1 | FORMULATIONS FOR GASTROINTESTINAL DELIVERY OF OLIGONUCLEOTIDES | MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) | 2021-04-15 | — | — | WO | disclosed |
| US-20210106525-A1 | FORMULATIONS FOR GASTROINTESTINAL DELIVERY OF OLIGONUCLEOTIDES | THE BRIGHAM AND WOMEN'S HOSPITAL, INC. | 2021-04-15 | — | — | US | disclosed |
| EP-3675838-A1 | LYMPHATIC SYSTEM-DIRECTING LIPID PRODRUGS | Puretecch LYT, Inc. (US) | 2020-07-08 | — | — | EP | disclosed |
| WO-2019046491-A1 | LYMPHATIC SYSTEM-DIRECTING LIPID PRODRUGS | ARIYA THERAPEUTICS, INC. (US) | 2019-03-07 | — | — | WO | disclosed |
| US-8314231-B2 | Systems, compositions, and/or methods for depolymerizing cellulose and/or starch | HYDRITE CHEMICAL CO. (US) | 2012-11-20 | — | — | US | disclosed |
| US-8314231-B2 | Systems, compositions, and/or methods for depolymerizing cellulose and/or starch | HYDRITE CHEMICAL CO. (US) | 2012-11-20 | — | — | US | disclosed |
| US-20100311139-A1 | SYSTEMS, COMPOSITIONS, AND/OR METHODS FOR DEPOLYMERIZING CELLULOSE AND/OR STARCH | BIOSYSTEMS CONSULTING, INC. DBA ADVANCED OXIDATION TECHNOLOGY | 2010-12-09 | — | — | US | disclosed |
| US-20100311139-A1 | SYSTEMS, COMPOSITIONS, AND/OR METHODS FOR DEPOLYMERIZING CELLULOSE AND/OR STARCH | BIOSYSTEMS CONSULTING, INC. DBA ADVANCED OXIDATION TECHNOLOGY | 2010-12-09 | — | — | US | disclosed |
| WO-2008137517-A1 | SYSTEMS, COMPOSITIONS, AND/OR METHODS FOR DEPOLYMERIZING CELLULOSE AND/OR STARCH | HYDRITE CHEMICAL CO. (US) | 2008-11-13 | — | — | WO | disclosed |
| WO-2008137517-A1 | SYSTEMS, COMPOSITIONS, AND/OR METHODS FOR DEPOLYMERIZING CELLULOSE AND/OR STARCH | HYDRITE CHEMICAL CO. (US) | 2008-11-13 | — | — | WO | disclosed |