Gluconic Acid

Gluconic Acid

SCHEMBL693435

O=C([O-])[C@H](O)[C@@H](O)[C@H](O)[C@H](O)CO.O=C([O-])[C@H](O)[C@@H](O)[C@H](O)[C@H](O)CO.O=C([O-])[C@H](O)[C@@H](O)[C@H](O)[C@H](O)CO.[Fe+2].[Na+]

nearest known ligand 0.95

Full drug profile on Sugi Atlas →

Known targets — ChEMBL curated mechanism

ACHESCN10ASCN11ASCN1ASCN2ASCN3ASCN4ASCN5ASCN7ASCN8ASCN9A

The experimentally established mechanism targets of Gluconic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
LMNA P02545 2/20 0.95
PDE4A P27815 1/20 0.64
L3MBTL1 Q9Y468 1/20 0.50
USP2 O75604 1/20 0.48
SLCO1B1 Q9Y6L6 1/20 0.48
TDP1 Q9NUW8 1/20 0.48
KDM4E B2RXH2 2/20 0.37
CA4 P22748 2/20 0.34
OR51E2 Q9H255 1/20 0.33
CYP2C9 P11712 1/20 0.32
TSHR P16473 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Gluconic Acid SCHEMBL27990997 1.00 LMNA (0.95) LMNAPDE4AL3MBTL1USP2SLCO1B1
Gluconic Acid SCHEMBL30213455 0.98 LMNA (1.00) LMNAPDE4AL3MBTL1USP2SLCO1B1
Gluconic Acid SCHEMBL31213255 0.98 LMNA (1.00) LMNAPDE4AL3MBTL1USP2SLCO1B1
Gluconic Acid SCHEMBL29431841 0.98 LMNA (1.00) LMNAPDE4AL3MBTL1USP2SLCO1B1
Gluconic Acid SCHEMBL3768836 0.98 LMNA (0.91) LMNAPDE4AL3MBTL1USP2SLCO1B1
Gluconic Acid SCHEMBL2572507 0.98 LMNA (1.00) LMNAPDE4AL3MBTL1USP2SLCO1B1
Gluconic Acid SCHEMBL9456606 0.98 LMNA (0.91) LMNAPDE4AL3MBTL1USP2SLCO1B1
Gluconic Acid SCHEMBL5065814 0.98 LMNA (1.00) LMNAPDE4AL3MBTL1USP2SLCO1B1
Gluconic Acid SCHEMBL23640 0.98 LMNA (1.00) LMNAPDE4AL3MBTL1USP2SLCO1B1
Gluconic Acid SCHEMBL35424 0.98 LMNA (0.91) LMNAPDE4AL3MBTL1USP2SLCO1B1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 91 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20090304816-A1 METHOD AND COMPOSITION FOR TREATING AND DIAGNOSING RESTLESS LEGS SYNDROME CEREUSCIENCE AB (SE) 2009-12-10 US claimed
EP-1973551-A1 METHOD AND COMPOSITION FOR TREATING AND DIAGNOSING RESTLESS LEGS SYNDROME Cereuscience AB (SE) 2008-10-01 EP claimed
EP-1827418-A2 COMPOSITIONS INCLUDING IRON Drugtech Corporation (US) 2007-09-05 EP claimed
EP-1827419-A2 METHODS AND COMPOSITIONS FOR ENHANCING IRON ABSORPTION Drugtech Corporation (US) 2007-09-05 EP claimed
WO-2007073325-A1 METHOD AND COMPOSITION FOR TREATING AND DIAGNOSING RESTLESS LEGS SYNDROME CEREUSCIENCE AB (SE) 2007-06-28 WO claimed
WO-2006068697-A2 COMPOSITIONS INCLUDING IRON DRUGTECH CORPORATION (US) 2006-06-29 WO claimed
WO-2006068729-A2 METHODS AND COMPOSITIONS FOR ENHANCING IRON ABSORPTION DRUGTECH CORPORATION (US) 2006-06-29 WO claimed
US-20060134227-A1 Compositions including iron DRUGTECH CORPORATION 2006-06-22 US claimed
WO-2003086321-A2 MODIFIED RELEASE MINERALS DRUGTECH CORPORATION (US) 2003-10-23 WO claimed
US-20030190355-A1 Modified release minerals DRUGTECH CORPORATION 2003-10-09 US claimed
CN-119488480-A Novel iron compositions and methods of making and using the same 雷尼布斯治疗公司 2025-02-21 CN disclosed
CN-116636620-B Black egg white peptide composition and application thereof 南昌大学 2025-02-14 CN disclosed
WO-2024263116-A1 A STABLE CAPSULE COMPOSITION WITH GASTRO-RESISTANT PELLETS FOR THE TREATMENT OF IRON DEFICIENCY ANEMIA ILKO ILAC SANAYI VE TICARET A.S. (TR) 2024-12-26 WO disclosed
CN-113825496-B Novel iron compositions and methods of making and using the same 雷尼布斯治疗公司 2024-09-27 CN disclosed
WO-2023119230-A1 COAGULATION PATHWAY AND NICOTINAMIDE-ADENINE DINUCLEOTIDE PATHWAY MODULATING COMPOSITIONS AND METHODS OF THEIR USE L'OREAL (FR) 2023-06-29 WO disclosed
WO-2006068697-A2 COMPOSITIONS INCLUDING IRON DRUGTECH CORPORATION (US) 2006-06-29 WO disclosed
US-20060134227-A1 Compositions including iron DRUGTECH CORPORATION 2006-06-22 US disclosed
US-20050037065-A1 NUTRITIONAL FORMULATIONS DRUGTECH CORPORATION (US) 2005-02-17 US disclosed
WO-2003086321-A2 MODIFIED RELEASE MINERALS DRUGTECH CORPORATION (US) 2003-10-23 WO disclosed
US-20030190355-A1 Modified release minerals DRUGTECH CORPORATION 2003-10-09 US disclosed