SCHEMBL3768880

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL3762914	0.92	L3MBTL3 (0.55)	ALDH1A1KDM4EPOLBSMN1; SMN2L3MBTL3
	SCHEMBL3762901	0.82	TSHR (0.55)	ALDH1A1TSHRKDM4EPOLBLMNA
	SCHEMBL3773907	0.81	KDM2B (0.53)	ALDH1A1KDM4EMEN1KMT2APOLB
	SCHEMBL3770797	0.81	L3MBTL3 (0.50)	ALDH1A1KDM4EMEN1KMT2APOLB
	SCHEMBL3767212	0.81	HTT (0.56)	ALDH1A1KDM4EPOLBL3MBTL3L3MBTL1
	SCHEMBL3773954	0.81	MEN1 (0.62)	ALDH1A1TSHRKDM4EMEN1KMT2A
	SCHEMBL3770368	0.81	KDM4E (0.67)	ALDH1A1KDM4EMEN1KMT2APOLB
	SCHEMBL3770129	0.81	ALDH1A1 (0.80)	ALDH1A1TSHRKDM4EMEN1KMT2A
	SCHEMBL3780472	0.80	ALDH1A1 (0.59)	ALDH1A1TSHRKDM4EMEN1KMT2A
	SCHEMBL13004967	0.79	KDM4E (0.62)	ALDH1A1KDM4EHRH3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.