SCHEMBL3769170

SCHEMBL3769170

Cc1ccc(OCCCOc2ccc3ccccc3c2)cc1

nearest known ligand 0.61

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
TDP1 Q9NUW8 3/20 0.61
KDM4E B2RXH2 2/20 0.61
MAPK1 P28482 1/20 0.61
NPC1 O15118 3/20 0.55
RAB9A P51151 3/20 0.55
DRD3 P35462 5/20 0.54
HRH3 Q9Y5N1 3/20 0.54
AGXT P21549 2/20 0.53
DRD2 P14416 4/20 0.53
DRD4 P21917 4/20 0.53
MAPT P10636 2/20 0.53
SMN1; SMN2 Q16637 1/20 0.53
PPARG P37231 1/20 0.53
CYP2A6 P11509 1/20 0.52
HTT P42858 1/20 0.51
ALDH1A1 P00352 1/20 0.50
ALOX5 P09917 1/20 0.50
POLB P06746 1/20 0.49
HDAC1 Q13547 1/20 0.49

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1728167 0.94 TDP1 (0.69) TDP1KDM4EMAPK1NPC1RAB9A
SCHEMBL29429997 0.88 TDP1 (0.76) TDP1KDM4EMAPK1NPC1RAB9A
SCHEMBL1859481 0.88 TDP1 (0.76) TDP1KDM4EMAPK1NPC1RAB9A
SCHEMBL9808305 0.86 TDP1 (0.68) TDP1KDM4EMAPK1NPC1RAB9A
SCHEMBL3991586 0.85 TDP1 (0.71) TDP1KDM4EMAPK1NPC1RAB9A
SCHEMBL8565990 0.84 TDP1 (0.76) TDP1KDM4EMAPK1NPC1RAB9A
SCHEMBL5701287 0.82 PPARG (0.79) TDP1KDM4EMAPK1NPC1RAB9A
SCHEMBL3806995 0.82 TDP1 (0.68) TDP1KDM4EMAPK1NPC1RAB9A
SCHEMBL470925 0.82 TDP1 (0.68) TDP1KDM4EMAPK1NPC1RAB9A
SCHEMBL29666114 0.82 TDP1 (0.68) TDP1KDM4EMAPK1NPC1RAB9A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-102712202-B Thermosensitive type lithographic plate and printing process thereof MITSUBISHI PAPER MILLS LTD. (JP) 2015-10-21 CN disclosed
US-8978553-B2 Heat-sensitive lithographic printing plates MITSUBISHI PAPER MILLS LIMITED (JP) 2015-03-17 US disclosed
CN-102712202-A Heat-sensitive lithographic printing plate and printing method thereof MITSUBISHI PAPER MILLS LTD 2012-10-03 CN disclosed
US-20120192740-A1 FOUNTAIN SOLUTION COMPOSITION FOR LITHOGRAPHIC PRINTING PLATE AND LITHOGRAPHIC PRINTING METHOD MITSUBISHI PAPER MILLS LIMITED (JP) 2012-08-02 US disclosed
US-20100307359-A1 HEAT-SENSITIVE LITHOGRAPHIC PRINTING PLATES MITSUBISHI PAPER MILLS LIMITED (JP) 2010-12-09 US disclosed
US-4985393-A Bis/hydroxyphenylthio/ Compounds KANZAKI PAPER MANUFACTURING CO., LTD. (JP) 1991-01-15 US disclosed