SCHEMBL1859481

SCHEMBL1859481

c1ccc2cc(OCCCOc3ccc4ccccc4c3)ccc2c1

nearest known ligand 0.76

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
TDP1 Q9NUW8 2/20 0.76
KDM4E B2RXH2 2/20 0.76
MAPK1 P28482 1/20 0.76
AGXT P21549 2/20 0.65
NPC1 O15118 3/20 0.63
RAB9A P51151 3/20 0.63
MAPT P10636 2/20 0.63
SMN1; SMN2 Q16637 1/20 0.63
ALOX5 P09917 1/20 0.61
HTT P42858 1/20 0.61
HRH3 Q9Y5N1 5/20 0.59
DRD3 P35462 2/20 0.59
PPARG P37231 2/20 0.58
HDAC1 Q13547 1/20 0.57
PTPN7 P35236 1/20 0.57
ALDH1A1 P00352 1/20 0.54
CYP1A2 P05177 1/20 0.54
CYP2A6 P11509 1/20 0.54

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29429997 1.00 TDP1 (0.76) TDP1KDM4EMAPK1AGXTNPC1
SCHEMBL8565990 0.95 TDP1 (0.76) TDP1KDM4EMAPK1AGXTNPC1
SCHEMBL9808305 0.94 TDP1 (0.68) TDP1KDM4EMAPK1AGXTNPC1
SCHEMBL16902857 0.93 TDP1 (0.73) TDP1KDM4EMAPK1AGXTNPC1
SCHEMBL16902871 0.93 TDP1 (0.73) TDP1KDM4EMAPK1AGXTNPC1
SCHEMBL16902850 0.93 TDP1 (0.73) TDP1KDM4EMAPK1AGXTNPC1
SCHEMBL16902859 0.93 TDP1 (0.73) TDP1KDM4EMAPK1AGXTNPC1
SCHEMBL16902858 0.93 TDP1 (0.73) TDP1KDM4EMAPK1AGXTNPC1
SCHEMBL16902870 0.93 TDP1 (0.73) TDP1KDM4EMAPK1AGXTNPC1
SCHEMBL16902856 0.93 TDP1 (0.73) TDP1KDM4EMAPK1AGXTNPC1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 78 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1160094-B1 Heat-sensitive recording material OJI PAPER CO (JP) 2003-09-03 EP claimed
US-20020006869-A1 Heat-sensitive recording material OJI PAPER CO., LTD. (JP) 2002-01-17 US claimed
EP-1160094-A2 Heat-sensitive recording material Oji Paper Co., Ltd. (JP) 2001-12-05 EP claimed
EP-0798127-A1 Heat sensitive recording material and method of using it Oji Paper Co., Ltd. (JP) 1997-10-01 EP claimed
JP-9263061-A None JP disclosed
JP-10086528-A None JP disclosed
JP-9314993-A None JP disclosed
JP-10035109-A None JP disclosed
EP-4733081-A1 PRINTING INK FOR HEAT-SENSITIVE RECORDING MEDIA Oji Holdings Corporation (JP) 2026-04-29 EP disclosed
US-12528307-B2 Heat-sensitive recording body Oji Holdings Corporation (JP) 2026-01-20 US disclosed
EP-4644129-A1 HEAT-SENSITIVE RECORDING BODY Oji Holdings Corporation (JP) 2025-11-05 EP disclosed
US-20250326242-A1 THERMOSENSITIVE RECORDING MEDIUM Oji Holdings Corporation (JP) 2025-10-23 US disclosed
EP-0826511-A1 Heat sensitive recording material Oji Paper Co., Ltd. (JP) 1998-03-04 EP disclosed
JP-H1035109-A HEAT-SENSITIVE RECORDING BODY AND ITS METHOD OF USE OJI PAPER CO LTD 1998-02-10 JP disclosed
JP-H09314993-A THERMAL RECORDING MATERIAL OJI PAPER CO LTD 1997-12-09 JP disclosed
JP-H09263061-A THERMAL RECORDING MATERIAL OJI PAPER CO LTD 1997-10-07 JP disclosed
EP-0798127-A1 Heat sensitive recording material and method of using it Oji Paper Co., Ltd. (JP) 1997-10-01 EP disclosed
EP-0798127-A1 Heat sensitive recording material and method of using it Oji Paper Co., Ltd. (JP) 1997-10-01 EP disclosed
EP-0774363-A1 Thermosensitive recording material OJI PAPER CO., LTD. (JP) 1997-05-21 EP disclosed
US-4115216-A QUARTERNARY AMMONIUM COMPOUNDS HOECHST AKTIENGESELLSCHAFT (DE) 1978-09-19 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12528307-B2 Heat-sensitive recording body LRBA, ARSA, HSPA4L TDP1 3369/4885KDM4E 4447/4885MAPK1 2166/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.