Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.70 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.70 |
| ▸ | MAPT | P10636 | 2/20 | 0.70 |
| ▸ | TP53 | P04637 | 1/20 | 0.64 |
| ▸ | KCNK3 | O14649 | 3/20 | 0.61 |
| ▸ | KCNK9 | Q9NPC2 | 3/20 | 0.61 |
| ▸ | PTGES | O14684 | 5/20 | 0.55 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.55 |
| ▸ | F2R | P25116 | 1/20 | 0.53 |
| ▸ | BCHE | P06276 | 1/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.52 |
| ▸ | PPARG | P37231 | 3/20 | 0.52 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.51 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3766559 | 0.91 | KCNK3 (0.66) | LMNASMN1; SMN2MAPTKCNK3KCNK9 | |
| SCHEMBL3769394 | 0.87 | KCNK3 (0.64) | LMNASMN1; SMN2MAPTTP53KCNK3 | |
| SCHEMBL3771423 | 0.87 | KCNK3 (0.61) | LMNASMN1; SMN2MAPTKCNK3KCNK9 | |
| SCHEMBL4258230 | 0.87 | SMN1; SMN2 (0.76) | LMNASMN1; SMN2MAPTTP53KCNK3 | |
| SCHEMBL3770493 | 0.86 | KCNK3 (0.60) | LMNASMN1; SMN2MAPTKCNK3KCNK9 | |
| SCHEMBL3769554 | 0.85 | KCNK3 (0.62) | LMNASMN1; SMN2MAPTTP53KCNK3 | |
| SCHEMBL3768813 | 0.85 | KCNK3 (0.61) | LMNASMN1; SMN2MAPTKCNK3KCNK9 | |
| SCHEMBL3768908 | 0.85 | MAPT (0.72) | LMNASMN1; SMN2MAPTKCNK3KCNK9 | |
| SCHEMBL3778616 | 0.85 | KCNK3 (0.57) | LMNASMN1; SMN2MAPTKCNK3KCNK9 | |
| SCHEMBL3772610 | 0.85 | KCNK3 (0.58) | LMNASMN1; SMN2MAPTKCNK3KCNK9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100324086-A1 | COMPOUNDS AND METHODS | NOVASAID AB (SE) | 2010-12-23 | — | — | US | claimed |
| WO-2009103778-A1 | COMPOUNDS AND METHODS | NOVASAID AB (SE) | 2009-08-27 | — | — | WO | claimed |
| US-20100324086-A1 | COMPOUNDS AND METHODS | NOVASAID AB (SE) | 2010-12-23 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100324086-A1 | COMPOUNDS AND METHODS | IL1B, LITAF, CYP11B1 | LMNA 2648/4885SMN1; SMN2 1085/4885MAPT 1426/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.