SCHEMBL3769728

SCHEMBL3769728

O=c1oc2c[c]ccc2[c]c1-c1nc2ccccc2[nH]1

nearest known ligand 0.48

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
NPC1 O15118 10/20 0.48
RAB9A P51151 9/20 0.48
MEN1 O00255 2/20 0.42
USP2 O75604 2/20 0.42
KMT2A Q03164 2/20 0.42
ATM Q13315 2/20 0.42
CASP3 P42574 1/20 0.42
SENP8 Q96LD8 1/20 0.42
SENP7 Q9BQF6 1/20 0.42
SENP6 Q9GZR1 1/20 0.42
TP53 P04637 5/20 0.42
KDM4E B2RXH2 5/20 0.42
ALDH1A1 P00352 5/20 0.42
SMN1; SMN2 Q16637 4/20 0.42
HSD17B10 Q99714 3/20 0.42
NPSR1 Q6W5P4 2/20 0.42
ABCB11 O95342 1/20 0.42
PKM P14618 1/20 0.42
LMNA P02545 2/20 0.40
POLB P06746 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6928197 0.77 RAB9A (0.73) NPC1RAB9AMEN1USP2KMT2A
Water SCHEMBL9817804 0.66 NPC1 (0.95) NPC1RAB9AUSP2TP53KDM4E
SCHEMBL2104393 0.65 NPC1 (0.72) NPC1RAB9AMEN1USP2KMT2A
SCHEMBL4583148 0.65 RAB9A (1.00) NPC1RAB9AMEN1USP2KMT2A
SCHEMBL979689 0.65 NPC1 (0.66) NPC1RAB9AMEN1USP2KMT2A
SCHEMBL15253735 0.65 F7 (0.55) NPC1RAB9AMEN1USP2KMT2A
SCHEMBL1704186 0.65 NPC1 (0.67) NPC1RAB9ATP53KDM4EALDH1A1
SCHEMBL27845522 0.64 NPC1 (0.70) NPC1RAB9AMEN1USP2KMT2A
SCHEMBL8487065 0.64 NPC1 (0.66) NPC1RAB9ATP53KDM4EALDH1A1
SCHEMBL30561047 0.64 NPC1 (1.00) NPC1RAB9AUSP2TP53KDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7846522-B2 Discoloration-resistant articles for applying color on surfaces and methods of reducing discoloration in articles for applying color on surfaces THE PROCTER & GAMBLE COMPANY (US) 2010-12-07 US disclosed
EP-1715997-A1 DISCOLORATION-RESISTANT ARTICLES FOR APPLYING COLOR ON SURFACES AND METHODS OF REDUCING DISCOLORATION IN ARTICLES FOR APPLYING COLOR ON SURFACES The Procter and Gamble Company (US) 2006-11-02 EP disclosed
US-20060046027-A1 Discoloration-resistant articles for applying color on surfaces and methods of reducing discoloration in articles for applying color on surfaces THE PROCTER & GAMBLE COMPANY (US) 2006-03-02 US disclosed
US-20060046028-A1 Discoloration-resistant articles for applying color on surfaces and methods of reducing discoloration in articles for applying color on surfaces THE PROCTER & GAMBLE COMPANY (US) 2006-03-02 US disclosed
WO-2005087492-A1 DISCOLORATION-RESISTANT ARTICLES FOR APPLYING COLOR ON SURFACES AND METHODS OF REDUCING DISCOLORATION IN ARTICLES FOR APPLYING COLOR ON SURFACES THE PROCTER & GAMBLE COMPANY (US) 2005-09-22 WO disclosed