SCHEMBL4583148

SCHEMBL4583148

O=c1oc2ccccc2cc1-c1nc2ccccc2[nH]1

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
RAB9A P51151 7/20 1.00
NPC1 O15118 7/20 1.00
USP2 O75604 3/20 0.68
MEN1 O00255 2/20 0.68
KMT2A Q03164 2/20 0.68
ATM Q13315 2/20 0.68
CASP3 P42574 1/20 0.68
SENP8 Q96LD8 1/20 0.68
SENP7 Q9BQF6 1/20 0.68
SENP6 Q9GZR1 1/20 0.68
TP53 P04637 6/20 0.67
MAPT P10636 6/20 0.67
CASP1 P29466 3/20 0.67
CASP7 P55210 3/20 0.67
LMNA P02545 2/20 0.67
BRCA1 P38398 2/20 0.67
HBB P68871 2/20 0.67
POLB P06746 1/20 0.67
HTT P42858 1/20 0.67
PTK2B Q14289 1/20 0.67

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Coumarin SCHEMBL28710843 0.92 RAB9A (0.85) RAB9ANPC1USP2MEN1KMT2A
SCHEMBL12814273 0.85 RAB9A (0.74) RAB9ANPC1USP2MEN1KMT2A
SCHEMBL6329610 0.85 RAB9A (0.74) RAB9ANPC1USP2MEN1KMT2A
SCHEMBL20917437 0.85 RAB9A (0.74) RAB9ANPC1USP2MEN1KMT2A
SCHEMBL24270308 0.85 RAB9A (0.74) RAB9ANPC1USP2MEN1KMT2A
SCHEMBL12388192 0.85 NPC1 (0.74) RAB9ANPC1USP2MEN1KMT2A
SCHEMBL8787220 0.85 NPC1 (0.74) RAB9ANPC1USP2MEN1KMT2A
SCHEMBL12388196 0.85 TP53 (0.81) RAB9ANPC1USP2MEN1KMT2A
SCHEMBL6928197 0.84 RAB9A (0.73) RAB9ANPC1USP2MEN1KMT2A
SCHEMBL8787494 0.83 RAB9A (0.71) RAB9ANPC1USP2MEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 140 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4663642-A1 POLYCYCLIC AROMATIC COMPOUND Kyoto University (JP) 2025-12-17 EP disclosed
US-12473315-B2 Polycyclic aromatic compound KWANSEI GAKUIN EDUCATIONAL FOUNDATION (JP) 2025-11-18 US disclosed
US-20250081847-A1 POLYCYCLIC AROMATIC COMPOUND KWANSEI GAKUIN EDUCATIONAL FOUNDATION (JP) 2025-03-06 US disclosed
US-12185625-B2 Organic electroluminescence element, display device, and lighting device KWANSEI GAKUIN EDUCATIONAL FOUNDATION (JP) 2024-12-31 US disclosed
US-20240360158-A1 POLYCYCLIC AROMATIC COMPOUND KWANSEI GAKUIN EDUCATIONAL FOUNDATION (JP) 2024-10-31 US disclosed
WO-2024166913-A1 POLYCYCLIC AROMATIC COMPOUND 国立大学法人京都大学 2024-08-15 WO disclosed
WO-2024080842-A1 ORGANOMETALLIC COMPOUND AND ORGANIC ELECTROLUMINESCENT DEVICE COMPRISING SAME 에스케이 주식회사 2024-04-18 WO disclosed
CN-117843662-A Polycyclic aromatic compound, material for organic device, organic electroluminescent element, display device, and lighting device 国立大学法人京都大学 2024-04-09 CN disclosed
US-11877506-B2 Polycyclic aromatic compound KWANSEI GAKUIN EDUCATIONAL FOUNDATION (JP) 2024-01-16 US disclosed
CN-117343089-A Polycyclic aromatic compound, material for organic device, organic electroluminescent element, display device, and lighting device 学校法人关西学院 2024-01-05 CN disclosed
US-20080160347-A1 Benzofluorene compound, emission materials and organic electroluminescent device JNC CORPORATION (JP) 2008-07-03 US disclosed
US-20080105865-A1 Pyrene Based Compound and Light Emitting Transistor Element Using the Same PIONEER CORPORATION (JP) 2008-05-08 US disclosed
US-20080012475-A1 Pyrene Based Compound, And Light Emitting Transistor Element And Electroluminescence Element Using The Same MITSUBISHI CHEMICAL CORPORATION (JP) 2008-01-17 US disclosed
CN-101080376-A Pyrene compound and light-emitting transistor element using same PIONEER CORP (JP) 2007-11-28 CN disclosed
CN-101072743-A Pyrene compound, and light-emitting transistor element and organic electroluminescent element using same PIONEER CORP (JP) 2007-11-14 CN disclosed
EP-1818322-A1 PYRENE COMPOUND AND, UTILIZING THE SAME, LIGHT EMITTING TRANSISTOR DEVICE AND ELECTROLUMINESCENCE DEVICE Rohm Co., Ltd. (JP) 2007-08-15 EP disclosed
EP-1816114-A1 PYRENE COMPOUND AND LIGHT EMITTING TRANSISTOR DEVICE UTILIZING THE SAME Rohm Co., Ltd. (JP) 2007-08-08 EP disclosed
US-5698575-A Chromone compounds, pharmaceutical compositions containing the same, and use of the same KUREHA CHEMICAL INDUSTRY CO., LTD. (JP) 1997-12-16 US disclosed
EP-0758649-A1 Chromone derivative, process for preparing same and pharmaceutical composition Kureha Chemical Industry Co., Ltd. (JP) 1997-02-19 EP disclosed
US-3985763-A DYESTUFFS BAYER AKTIENGESELLSCHAFT (DT) 1976-10-12 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (7 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20240360158-A1 POLYCYCLIC AROMATIC COMPOUND ETV6, EML4, ELOC RAB9A 3457/4885NPC1 1243/4885USP2 3714/4885
US-11877506-B2 Polycyclic aromatic compound F11, C1R, RNF31 RAB9A 3722/4885NPC1 1150/4885USP2 3198/4885
US-20080160347-A1 Benzofluorene compound, emission materials and organic electroluminescent device LEF1, TRPA1, BRD8 RAB9A 3119/4885NPC1 3547/4885USP2 4295/4885
US-20250081847-A1 POLYCYCLIC AROMATIC COMPOUND PAH, ALK, AOC2 RAB9A 3989/4885NPC1 3235/4885USP2 4113/4885
US-20080105865-A1 Pyrene Based Compound and Light Emitting Transistor Element Using the Same CYP1A1, SULT1A1, SULT1E1 RAB9A 1745/4885NPC1 715/4885USP2 4747/4885
US-12473315-B2 Polycyclic aromatic compound PAH, ALK, AOC2 RAB9A 3989/4885NPC1 3235/4885USP2 4113/4885
US-20080012475-A1 Pyrene Based Compound, And Light Emitting Transistor Element And Electroluminescence Element Using The Same ARNT, ESR1, TEAD4 RAB9A 2899/4885NPC1 348/4885USP2 4664/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.