Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.69 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.68 |
| ▸ | MAPT | P10636 | 7/20 | 0.68 |
| ▸ | HPGD | P15428 | 5/20 | 0.68 |
| ▸ | GAA | P10253 | 2/20 | 0.68 |
| ▸ | LMNA | P02545 | 1/20 | 0.68 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.61 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.54 |
| ▸ | HSD17B10 | Q99714 | 5/20 | 0.54 |
| ▸ | USP2 | O75604 | 1/20 | 0.54 |
| ▸ | ALOX15 | P16050 | 4/20 | 0.52 |
| ▸ | MEN1 | O00255 | 3/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.52 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.52 |
| ▸ | RECQL | P46063 | 1/20 | 0.50 |
| ▸ | ANO1 | Q5XXA6 | 1/20 | 0.49 |
| ▸ | TSHR | P16473 | 1/20 | 0.48 |
| ▸ | CASP1 | P29466 | 1/20 | 0.48 |
| ▸ | CASP7 | P55210 | 1/20 | 0.48 |
| ▸ | TLR2 | O60603 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL134682 | 0.97 | TDP1 (0.65) | TDP1ALDH1A1MAPTHPGDGAA | |
| SCHEMBL137057 | 0.85 | ALDH1A1 (0.68) | TDP1ALDH1A1MAPTHPGDGAA | |
| SCHEMBL138711 | 0.85 | TDP1 (0.74) | TDP1ALDH1A1MAPTHPGDGAA | |
| SCHEMBL4154525 | 0.84 | ALDH1A1 (0.67) | TDP1ALDH1A1MAPTHPGDGAA | |
| SCHEMBL135520 | 0.83 | TDP1 (0.64) | TDP1ALDH1A1MAPTHPGDGAA | |
| SCHEMBL3656064 | 0.83 | ALDH1A1 (0.81) | TDP1ALDH1A1MAPTHPGDGAA | |
| SCHEMBL3768107 | 0.82 | TDP1 (0.74) | TDP1ALDH1A1MAPTHPGDGAA | |
| SCHEMBL3768395 | 0.82 | TDP1 (0.74) | TDP1ALDH1A1MAPTHPGDGAA | |
| SCHEMBL136844 | 0.82 | TDP1 (0.74) | TDP1ALDH1A1MAPTHPGDGAA | |
| SCHEMBL4057532 | 0.82 | TDP1 (0.70) | TDP1ALDH1A1MAPTHPGDGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100317709-A1 | SPHINGOSINE-1-PHOSPHATE (S1P) RECEPTOR COMPOUNDS | UNIVERSITEIT LEIDEN | 2010-12-16 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100317709-A1 | SPHINGOSINE-1-PHOSPHATE (S1P) RECEPTOR COMPOUNDS | S1PR3, S1PR1, S1PR5 | TDP1 1316/4885ALDH1A1 4570/4885MAPT 4166/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.