Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 3/20 | 0.42 |
| ▸ | PNMT | P11086 | 2/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.38 |
| ▸ | CYP2A6 | P11509 | 2/20 | 0.38 |
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.35 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.35 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.34 |
| ▸ | IDO1 | P14902 | 2/20 | 0.34 |
| ▸ | GLA | P06280 | 1/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.32 |
| ▸ | DRD2 | P14416 | 2/20 | 0.31 |
| ▸ | DRD3 | P35462 | 2/20 | 0.31 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29957142 | 1.00 | TSHR (0.42) | TSHRPNMTCYP1A2CYP2A6LMNA | |
| Hydrochloric Acid SCHEMBL3291195 | 0.98 | TSHR (0.41) | TSHRPNMTCYP1A2CYP2A6LMNA | |
| SCHEMBL5588312 | 0.83 | CYP3A4 (0.41) | TSHRLMNACYP3A4TDP1 | |
| SCHEMBL5587839 | 0.83 | TSHR (0.32) | TSHRCYP1A2CYP2A6LMNA | |
| SCHEMBL5587462 | 0.83 | PNMT (0.33) | TSHRPNMTCYP1A2LMNAMEN1 | |
| SCHEMBL5590657 | 0.83 | CYP3A4 (0.41) | TSHRLMNACYP3A4TDP1 | |
| SCHEMBL29953266 | 0.79 | — | — | |
| SCHEMBL653876 | 0.79 | — | — | |
| SCHEMBL8436824 | 0.77 | CYP3A4 (0.40) | CYP2A6CYP3A4TDP1 | |
| Hydrochloric Acid SCHEMBL8436823 | 0.77 | TSHR (0.45) | TSHRPNMTCYP1A2CYP2A6LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 142 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20170320908-A1 | SOLID PHASE SYNTHESIS OF CYCLIC AMINO ACID MOLECULES | ENCYCLE THERAPEUTICS INC. (CA) | 2017-11-09 | — | — | US | claimed |
| EP-3221335-A1 | SOLID PHASE SYNTHESIS OF CYCLIC AMINO ACID MOLECULES | Encycle Therapeutics (CA) | 2017-09-27 | — | — | EP | claimed |
| WO-2016079682-A1 | SOLID PHASE SYNTHESIS OF CYCLIC AMINO ACID MOLECULES | ENCYCLE THERAPEUTICS (CA) | 2016-05-26 | — | — | WO | claimed |
| US-9260479-B2 | Cyclic amino acid molecules and methods of preparing the same | THE GOVERNING COUNCIL OF THE UNIVERSITY OF TORONTO (CA) | 2016-02-16 | — | — | US | claimed |
| WO-2012109735-A1 | METHODS OF PREPARING CYCLIC AMINO ACID MOLECULES USING ARYLBORONIC OR ARYLBORINIC ACID CATALYSTS | THE GOVERNING COUNCIL OF THE UNIVERSITY OF TORONTO (CA) | 2012-08-23 | — | — | WO | claimed |
| US-20120065366-A1 | CYCLIC AMINO ACID MOLECULES AND METHODS OF PREPARING THE SAME | THE GOVERNING COUNCIL OF THE UNIVERSITY OF TORONTO (CA) | 2012-03-15 | — | — | US | claimed |
| EP-2408802-A1 | CYCLIC AMINO ACID MOLECULES AND METHODS OF PREPARING THE SAME | The Governing Council of the University of Toronto (CA) | 2012-01-25 | — | — | EP | claimed |
| WO-2010105363-A1 | CYCLIC AMINO ACID MOLECULES AND METHODS OF PREPARING THE SAME | YUDIN ANDREI (CA) | 2010-09-23 | — | — | WO | claimed |
| EP-0039905-B1 | PROCESS FOR THE PREPARATION OF 2-CHLORO-BENZOTHIAZOLE | CASSELLA Aktiengesellschaft (DE) | 1983-11-02 | — | — | EP | claimed |
| EP-0039905-A1 | Process for the preparation of 2-chloro-benzothiazole | CASSELLA Aktiengesellschaft (DE) | 1981-11-18 | — | — | EP | claimed |
| JP-4210952-A | — | — | None | — | — | JP | disclosed |
| US-10385099-B2 | Cyclic amino acid molecules and methods of preparing the same | THE GOVERNING COUNCIL OF THE UNIVERSITY OF TORONTO (CA) | 2019-08-20 | — | — | US | disclosed |
| US-20170320908-A1 | SOLID PHASE SYNTHESIS OF CYCLIC AMINO ACID MOLECULES | ENCYCLE THERAPEUTICS INC. (CA) | 2017-11-09 | — | — | US | disclosed |
| EP-3221335-A1 | SOLID PHASE SYNTHESIS OF CYCLIC AMINO ACID MOLECULES | Encycle Therapeutics (CA) | 2017-09-27 | — | — | EP | disclosed |
| EP-2408802-B1 | CYCLIC AMINO ACID MOLECULES AND METHODS OF PREPARING THE SAME | GOVERNING COUNCIL UNIV TORONTO (CA) | 2017-05-03 | — | — | EP | disclosed |
| US-4088629-A | ADDING A PIPERIDINYL-GUANIDINE | BAYER AKTIENGESELLSCHAFT (DT) | 1978-05-09 | — | — | US | disclosed |
| US-4082761-A | CENTRAL NERVOUS SYSTEM DEPRESSANTS | THE UPJOHN COMPANY (US) | 1978-04-04 | — | — | US | disclosed |
| US-4057637-A | RHEUMATOID ARTHRITIS | MERCK & CO., INC. (US) | 1977-11-08 | — | — | US | disclosed |
| US-4025532-A | CHEMOSTERILANTS | AMERICAN CYANAMID COMPANY (US) | 1977-05-24 | — | — | US | disclosed |
| US-3971797-A | ANTIARTHRITIC | MERCK & CO., INC. (US) | 1976-07-27 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120065366-A1 | CYCLIC AMINO ACID MOLECULES AND METHODS OF PREPARING THE SAME | DNPEP, ANPEP, BCAT1 | TSHR 2991/4885PNMT 1311/4885CYP1A2 4217/4885 |
| US-10385099-B2 | Cyclic amino acid molecules and methods of preparing the same | DNPEP, ANPEP, BCAT1 | TSHR 2991/4885PNMT 1311/4885CYP1A2 4217/4885 |
| US-20170320908-A1 | SOLID PHASE SYNTHESIS OF CYCLIC AMINO ACID MOLECULES | MAX, BCAT1, ASNS | TSHR 1768/4885PNMT 1612/4885CYP1A2 4439/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.