SCHEMBL3770243

SCHEMBL3770243

CC(C)C(=O)C1=CCCC1=O

nearest known ligand 0.35

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
CYP1A2 P05177 1/20 0.35
ALDH1A1 P00352 1/20 0.33
FFAR1 O14842 1/20 0.32
PTPN1 P18031 1/20 0.31
KDM4E B2RXH2 1/20 0.31
DBH P09172 1/20 0.31
GAA P10253 1/20 0.31
RECQL P46063 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5170282 0.79 ALDH1A1 (0.37) CYP1A2ALDH1A1PTPN1
SCHEMBL13508754 0.76
SCHEMBL4194302 0.73
SCHEMBL15468834 0.73
SCHEMBL4544245 0.71
SCHEMBL8569125 0.71 PTPN1 (0.41) CYP1A2ALDH1A1PTPN1
SCHEMBL15957896 0.68 PTPN1 (0.39) CYP1A2PTPN1RECQL
SCHEMBL5178286 0.67 ALDH1A1 (0.47) CYP1A2ALDH1A1
SCHEMBL1044726 0.66
SCHEMBL15957919 0.64 PTPN1 (0.52) ALDH1A1PTPN1RECQL

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2010068731-A1 A METHOD FOR THE PURIFICATION OF SUBSTITUTED CYCLOPENT-2-EN-1-ONE CONGENERS AND SUBSTITUTED 1,3-CYCLOPENTADIONE CONGENERS FROM A COMPLEX MIXTURE USING COUNTERCURRENT SEPARATION METAPROTEOMICS, LLC (US) 2010-06-17 WO disclosed
CN-1250211-C Remediesor preventives containing cyclopentenone compounds as the active ingredient TAKARA SHUZO CO (JP) 2006-04-12 CN disclosed
CN-1323204-A Therapeutic or prophylactic agent comprising cyclopentenone compound as active ingredient TAKARA SHUZO CO (JP) 2001-11-21 CN disclosed