SCHEMBL5178286

SCHEMBL5178286

CC(C)C(O)C1=CCCC1=O

nearest known ligand 0.47

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 1/20 0.47
CYP1A2 P05177 1/20 0.42
HIF1A Q16665 1/20 0.40
TP53 P04637 1/20 0.38
MAPT P10636 1/20 0.37
THRB P10828 1/20 0.34
ALOX15 P16050 2/20 0.33
CYP3A4 P08684 1/20 0.33
CYP2C19 P33261 2/20 0.31
CYP2C9 P11712 1/20 0.31
TSHR P16473 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4120017 0.88 HIF1A (0.53) ALDH1A1CYP1A2HIF1ATP53MAPT
SCHEMBL13043858 0.88 HIF1A (0.53) ALDH1A1CYP1A2HIF1ATP53MAPT
SCHEMBL1044726 0.80
SCHEMBL11759184 0.79 ALDH1A1 (0.47) ALDH1A1CYP1A2HIF1ATP53MAPT
SCHEMBL4444002 0.79 ALDH1A1 (0.51) ALDH1A1CYP1A2HIF1ATP53MAPT
SCHEMBL12056719 0.71 HIF1A (0.56) ALDH1A1CYP1A2HIF1ATP53MAPT
SCHEMBL1238217 0.71 CYP1A2 (0.42) ALDH1A1CYP1A2HIF1ATP53MAPT
SCHEMBL6548167 0.70 HIF1A (0.50) ALDH1A1CYP1A2HIF1ATP53MAPT
SCHEMBL4442531 0.69 TP53 (0.55) ALDH1A1CYP1A2HIF1ATP53MAPT
SCHEMBL5179413 0.68 TP53 (0.58) ALDH1A1CYP1A2HIF1ATP53ALOX15

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1791804-A1 2-ALKYLIDENE- AND 2-(ALKYL-1-ENE)-CYCLOPENTANONE AS PERFUMES Symrise GmbH & Co. KG (DE) 2007-06-06 EP disclosed
WO-2006030010-A1 2-ALKYLIDENE- AND 2-(ALKYL-1-ENE)-CYCLOPENTANONE AS PERFUMES SYMRISE GMBH & CO. KG (DE) 2006-03-23 WO disclosed