Sugi Predict

Sugi Predict / Compounds / SCHEMBL377032

SCHEMBL377032

SCHEMBL377032

Cc1ccc(N)c([N+](=O)[O-])c1C

nearest known ligand 0.60

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
▸ TSHR P16473 7/20 0.55
▸ CYP3A4 P08684 4/20 0.55
▸ ALDH1A1 P00352 8/20 0.52
▸ TDP1 Q9NUW8 6/20 0.52
▸ RECQL P46063 1/20 0.46
▸ SMN1; SMN2 Q16637 1/20 0.44
▸ MEN1 O00255 2/20 0.43
▸ KMT2A Q03164 2/20 0.43
▸ USP2 O75604 1/20 0.43
▸ KEAP1 Q14145 1/20 0.43
▸ NFE2L2 Q16236 1/20 0.43
▸ TP53 P04637 1/20 0.41
▸ ACHE P22303 1/20 0.40
▸ HSD17B10 Q99714 1/20 0.40
▸ POLB P06746 1/20 0.39
▸ MAPT P10636 1/20 0.39
▸ ALOX15 P16050 1/20 0.39
▸ HTT P42858 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6513444 0.87 TDP1 (0.50) TSHRCYP3A4ALDH1A1TDP1RECQL
SCHEMBL938653 0.85 TSHR (0.57) TSHRCYP3A4ALDH1A1TDP1RECQL
SCHEMBL2056645 0.83 TSHR (0.55) TSHRCYP3A4ALDH1A1TDP1RECQL
SCHEMBL823521 0.83 TSHR (0.55) TSHRCYP3A4ALDH1A1TDP1RECQL
SCHEMBL3192684 0.82 ALDH1A1 (0.62) TSHRCYP3A4ALDH1A1TDP1RECQL
SCHEMBL2006430 0.82 TSHR (0.53) TSHRCYP3A4ALDH1A1TDP1RECQL
SCHEMBL2371812 0.80 TSHR (0.52) TSHRCYP3A4ALDH1A1TDP1RECQL
SCHEMBL20571586 0.80 TSHR (0.52) TSHRCYP3A4ALDH1A1TDP1RECQL
SCHEMBL16029635 0.80 ALDH1A1 (0.48) TSHRCYP3A4ALDH1A1TDP1MEN1
SCHEMBL5704996 0.80 TSHR (0.52) TSHRCYP3A4ALDH1A1TDP1RECQL

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 78 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7539006-B2 Electrolytic solution for driving electrolytic capacitor and electrolytic capacitor RUBYCON CORPORATION (JP) 2009-05-26 — — US claimed
CN-100456398-C Electrolyte for driving electrolytic capacitor and electrolytic capacitor RUBYCON CORP (JP) 2009-01-28 — — CN claimed
US-20070029529-A1 Electrolytic solution for driving electrolytic capacitor and electrolytic capacitor KOMATSU AKIHIKO 2007-02-08 — — US claimed
CN-1228317-C Synthesis of carbamate through low pressure heterogeneous oxidative carbonylation of amines UNIV AKRON (US) 2005-11-23 — — CN claimed
US-20040245105-A1 Electrolyte solution for driving electrolytic capacitor and electrolytic capacitor RUBYCON CORPORATION (JP) 2004-12-09 — — US claimed
CN-1529892-A Electrolyte for driving electrolytic capacitor and electrolytic capacitor 如碧空株式会社 2004-09-15 — — CN claimed
CN-1520394-A Synthesis of carbamates by low pressure heterogeneous oxidative carbonylation of amines �����״�ѧ 2004-08-11 — — CN claimed
EP-1437749-A1 ELECTROLYTE SOLUTION FOR DRIVING ELECTROLYTIC CAPACITOR AND ELECTROLYTIC CAPACITOR Rubycon Corporation (JP) 2004-07-14 — — EP claimed
US-6541653-B2 Reacting an amine, alcohol, oxygen, and carbon monoxide in the gaseous state in the presence of a solid catalytic system of a group VIII metal catalysts and/or copper-based catalysts with halide promoters AKRON, UNIVERSITY OF, THE 2003-04-01 — — US claimed
US-20020183541-A1 SYNTHESIS OF CARBAMATE THROUGH LOW PRESSURE HETEROGENEOUS OXIDATIVE CARBONYLATION OF AMINES AKRON, UNIVERSITY OF, THE 2002-12-05 — — US claimed
WO-2002088050-A2 SYNTHESIS OF CARBAMATE THROUGH LOW PRESSURE HETEROGENEOUS OXIDATIVE CARBONYLATION OF AMINES THE UNIVERSITY OF AKRON (US) 2002-11-07 — — WO claimed
WO-2025072721-A1 COMPOSITIONS UVAGELESS LLC (US) 2025-04-03 — — WO disclosed
CN-115255358-B Surface modification method of metal powder material, modified metal powder material and application of modified metal powder material 西安隆基乐叶光伏科技有限公司 2024-01-16 — — CN disclosed
CN-115255358-A Surface modification method of metal powder material, modified metal powder material and application thereof 西安隆基乐叶光伏科技有限公司 2022-11-01 — — CN disclosed
CN-105819225-B A kind of preparation method for manganese slag lightweight ceramic tile automatic charging device and its critical component 徐州工程学院 2017-12-26 — — CN disclosed
EP-0315178-A2 Process for producing a urethane and a carbonic acid ester MITSUBISHI GAS CHEMICAL COMPANY, INC. (JP) 1989-05-10 — — EP disclosed
US-4582923-A REACTING PRIMARY AMINE, CARBON MONOXIDE AND HYDROXYL COMPOUND IN PRESENCE OF PALLADIUM OR PALLADIUM COMPOUND AND OXIDIZING QUINOID, REDOX CATALYSIS BAYER AKTIENGESELLSCHAFT (DE) 1986-04-15 — — US disclosed
EP-0054105-B1 PROCESS FOR THE PREPARATION OF POLYESTERS MODIFIED BY (METH)ACRYLIC ACID Vianova Kunstharz Aktiengesellschaft (AT) 1984-12-05 — — EP disclosed
EP-0054105-A1 Process for the preparation of polyesters modified by (meth)acrylic acid Vianova Kunstharz Aktiengesellschaft (AT) 1982-06-23 — — EP disclosed
US-4153505-A PYROLYZED AROMATIC NITROGEN-CONTAINING THERMOSET FOAM MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1979-05-08 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20020183541-A1 SYNTHESIS OF CARBAMATE THROUGH LOW PRESSURE HETEROGENEOUS OXIDATIVE CARBONYLATION OF AMINES SOD1, CAT, CA4 TSHR 3743/4885CYP3A4 402/4885ALDH1A1 1280/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.